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Merck

PDHB

pyruvate dehydrogenase (lipoamide) beta

Sinonimi:
PDHBD, PDHE1-B, PHE1B
Specie:
ID UniProtKB:
ID gene:
  • Human(5162) Summary: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
  • Mouse(68263) pyruvate dehydrogenase (lipoamide) beta
  • Rat(289950) pyruvate dehydrogenase (lipoamide) beta
  • cow(613610) pyruvate dehydrogenase (lipoamide) beta
  • sheep(101121975) pyruvate dehydrogenase (lipoamide) beta
  • domestic guinea pig(100733476) pyruvate dehydrogenase (lipoamide) beta
  • naked mole-rat(101714134) pyruvate dehydrogenase (lipoamide) beta
  • Zebrafish(406428) pyruvate dehydrogenase (lipoamide) beta
  • Horse(100050581) pyruvate dehydrogenase (lipoamide) beta
  • domestic cat(101100374) pyruvate dehydrogenase (lipoamide) beta
  • dog(476574) pyruvate dehydrogenase (lipoamide) beta
  • chicken(416066) pyruvate dehydrogenase (lipoamide) beta

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PDHB antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
immunohistochemistry
western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-PDHB antibody produced in mouse, clone 1D1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
Anti-PDHB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
immunofluorescence
western blot

Kits

N° Catalogo
Descrizione
Specie
Pyruvate Dehydrogenase Activity Assay Kit, sufficient for 100 colorimetric tests,
Specie
rat, mouse, human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human PDHB,
Specie
human
MISSION® esiRNA, targeting mouse Pdhb,
Specie
mouse