KCNQ4
potassium voltage-gated channel, KQT-like subfamily, member 4
Sinonimi:
DFNA2, DFNA2A, KV7.4
Specie:
Human KCNQ4 (9132), Mouse Kcnq4 (60613), Rat Kcnq4 (298496), sheep KCNQ4 (101122655), Domestic Rabbit KCNQ4 (100358271), domestic guinea pig Kcnq4 (100716024), naked mole-rat Kcnq4 (101714294), chicken KCNQ4 (419643), domestic cat KCNQ4 (101091641), Horse KCNQ4 (100067963) ...Più
ID UniProtKB:
ID gene:
- Human(9132) Summary: The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(60613) potassium voltage-gated channel, subfamily Q, member 4
- Rat(298496) potassium voltage-gated channel, KQT-like subfamily, member 4
- sheep(101122655) potassium voltage-gated channel, KQT-like subfamily, member 4
- Domestic Rabbit(100358271) potassium voltage-gated channel, KQT-like subfamily, member 4
- domestic guinea pig(100716024) potassium voltage-gated channel, KQT-like subfamily, member 4
- naked mole-rat(101714294) potassium voltage-gated channel, KQT-like subfamily, member 4
- chicken(419643) potassium voltage-gated channel, KQT-like subfamily, member 4
- domestic cat(101091641) potassium voltage-gated channel, KQT-like subfamily, member 4
- Horse(100067963) potassium voltage-gated channel, KQT-like subfamily, member 4
- cow(528741) potassium voltage-gated channel, KQT-like subfamily, member 4
- dog(482451) potassium voltage-gated channel, KQT-like subfamily, member 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Activator
N° Catalogo
Descrizione
Specie
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-KCNQ4 antibody produced in mouse, clone 2H6, purified immunoglobulin, buffered aqueous solution,
Reattività con
mouse
Applicazione
ELISA
western blot
western blot
Anti-KCNQ4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
western blot
Small Molecule - Blocker
Small Molecule - Inhibitor
N° Catalogo
Descrizione
Specie