F8
coagulation factor VIII, procoagulant component
Sinonimi:
AHF, DXS1253E, F8B, F8C, FVIII, HEMA
Specie:
Human F8 (2157), Mouse F8 (14069), Rat F8 (302470), Zebrafish f8 (100302404), chicken F8 (422199), cow F8 (100271720), domestic cat F8 (101092751), dog F8 (403875), sheep F8 (100359363), Domestic Rabbit F8 (100303761) ...Più
ID UniProtKB:
ID gene:
- Human(2157) Summary: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
- Mouse(14069) coagulation factor VIII
- Rat(302470) coagulation factor VIII, procoagulant component
- Zebrafish(100302404) coagulation factor VIII, procoagulant component
- chicken(422199) coagulation factor VIII, procoagulant component
- cow(100271720) coagulation factor VIII, procoagulant component
- domestic cat(101092751) coagulation factor VIII, procoagulant component
- dog(403875) coagulation factor VIII, procoagulant component
- sheep(100359363) coagulation factor VIII, procoagulant component
- Domestic Rabbit(100303761) coagulation factor VIII, procoagulant component
- domestic guinea pig(100720831) coagulation factor VIII, procoagulant component
- naked mole-rat(101725450) coagulation factor VIII, procoagulant component
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Factor VIII antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
ELISA
western blot
western blot
Anti-F8 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Monoclonal Anti-F8 antibody produced in mouse, clone 5E9B2, ascites fluid,
Reattività con
human
Applicazione
ELISA
western blot
western blot
Anticorpo anti-fattore VIII, clone GMA-012, clone GMA-012, Upstate®, from mouse,
Reattività con
human
Applicazione
ELISA
western blot
western blot
Anti-Factor VIII Antibody, 83 kDa light chain, ascites fluid, Chemicon®,
Reattività con
human
Applicazione
ELISA
western blot
western blot
esiRNA
N° Catalogo
Descrizione
Specie