EGFR
epidermal growth factor receptor
Sinonimi:
ERBB, ERBB1, HER1, PIG61, mENA
Specie:
Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), fruit fly Egfr (37455), cow EGFR (407217), Horse EGFR (100067755), domestic cat EGFR (100510799), dog EGFR (404306), chicken EGFR (396494), domestic guinea pig Egfr (100725363) ...Più
ID UniProtKB:
ID gene:
- Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(13649) epidermal growth factor receptor
- Rat(24329) epidermal growth factor receptor
- fruit fly(37455) Epidermal growth factor receptor
- cow(407217) epidermal growth factor receptor
- Horse(100067755) epidermal growth factor receptor
- domestic cat(100510799) epidermal growth factor receptor
- dog(404306) epidermal growth factor receptor
- chicken(396494) epidermal growth factor receptor
- domestic guinea pig(100725363) epidermal growth factor receptor
- naked mole-rat(101723771) epidermal growth factor receptor
- sheep(780479) epidermal growth factor receptor
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ELISA
N° Catalogo
Descrizione
Specie
Human EGFR / ErbB1 ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Specie
human
Phospho-EGFR (pTyr1068) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr1068) and pan-egfr in cell and tissue lysates,
Specie
human
Phospho-EGFR (pTyr1068) ELISA Kit, for detection of human phospho-egfr (pTyr1068) in cell and tissue lysates,
Specie
human
Small Molecule - Antagonist
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-EGFR PE produced in mouse, ,
Reattività con
horse
Applicazione
flow cytometry
Anti-EGFRvIII Antibody, clone DH8.3, clone DH8.3, from mouse,
Reattività con
human
Applicazione
ELISA
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anticorpo anti-EGFR, clone LA22, clone LA22, Upstate®, from mouse,
Reattività con
human
Applicazione
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-EGFR Antibody, neutralizing, clone LA1, clone LA1, Upstate®, from mouse,
Reattività con
human
Applicazione
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
neutralization
western blot
immunohistochemistry
immunoprecipitation (IP)
neutralization
western blot
Anti-dEGF Receptor, Extracellular Domain antibody, Mouse monoclonal, clone C-273, purified from hybridoma cell culture,
Reattività con
drosophila
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
N° Catalogo
Descrizione
Specie
Epidermal Growth Factor Receptor human, lyophilized powder, ≥15,000 units/mg protein (Bradford),
Specie
human
EGFR Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Specie
human
EGFR (T790M L858R) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Specie
human
EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Specie
human
Epidermal Growth Factor Receptor human, buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry),
Specie
human