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Merck

APEX1

APEX nuclease (multifunctional DNA repair enzyme) 1

Sinonimi:
APE, APE1, APEN, APEX, APX, HAP1, REF1
Specie:
ID UniProtKB:
ID gene:
  • Human(328) Summary: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(11792) apurinic/apyrimidinic endonuclease 1
  • Rat(79116) APEX nuclease (multifunctional DNA repair enzyme) 1
  • Zebrafish(406730) APEX nuclease (multifunctional DNA repair enzyme) 1
  • cow(281630) APEX nuclease (multifunctional DNA repair enzyme) 1
  • domestic cat(101101318) APEX nuclease (multifunctional DNA repair enzyme) 1
  • dog(482558) APEX nuclease (multifunctional DNA repair enzyme) 1
  • chicken(100431102) APEX nuclease (multifunctional DNA repair enzyme) 1
  • Goat(100860967) APEX nuclease (multifunctional DNA repair enzyme) 1
  • sheep(101115462) APEX nuclease (multifunctional DNA repair enzyme) 1
  • naked mole-rat(101709711) APEX nuclease (multifunctional DNA repair enzyme) 1
  • domestic guinea pig(100719062) APEX nuclease (multifunctional DNA repair enzyme) 1

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Antibodies

Product Number
Descrizione
Reattività con
Applicazione
Anti-APEX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-APEX1 antibody produced in rabbit, ,
Reattività con
human
Applicazione
immunofluorescence
immunoprecipitation (IP)

western blot
Monoclonal Anti-APEX1 antibody produced in mouse, clone 4D1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
Anti-APEX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Monoclonal Anti-APEX1 antibody produced in mouse, clone 3E12, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunoprecipitation (IP)

esiRNA

Product Number
Descrizione
Specie
MISSION® esiRNA, targeting human APEX1,
Specie
human
MISSION® esiRNA, targeting mouse Apex1,
Specie
mouse