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1631001

USP

Sulfamethoxazole

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

4-amino-N-(5-méthyl-3-isoxazolyl)benzènesulfonamide

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About This Item

Formule empirique (notation de Hill):
C10H11N3O3S
Numéro CAS:
723-46-6
Poids moléculaire :
253.28
Numéro Beilstein :
6732984
Numéro MDL:
MFCD00010546
Code UNSPSC :
41116107
ID de substance PubChem :
329751182
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

sulfamethoxazole

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1

InChI

1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

Clé InChI

JLKIGFTWXXRPMT-UHFFFAOYSA-N

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sulfamethoxazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Sulfamethoxazole Oral Suspension
  • Sulfamethoxazole and Trimethoprim Tablets
  • Sulfamethoxazole and Trimethoprim Injection
  • Sulfamethoxazole and Trimethoprim Oral Suspension

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1631500

Sulfamethoxazole N4-glucoside, United States Pharmacopeia (USP) Reference Standard

Y0000412

Sulfamethoxazole impurity A, European Pharmacopoeia (EP) Reference Standard

Y0000413

Sulfamethoxazole impurity F, European Pharmacopoeia (EP) Reference Standard

S2100000

Sulfamethoxazole, European Pharmacopoeia (EP) Reference Standard

1631533

Sulfamethoxazole Related Compound C, United States Pharmacopeia (USP) Reference Standard

1631511

Sulfamethoxazole Related Compound A, United States Pharmacopeia (USP) Reference Standard

1631566

Sulfamethoxazole Related Compound F, United States Pharmacopeia (USP) Reference Standard

1631522

Sulfamethoxazole Related Compound B, United States Pharmacopeia (USP) Reference Standard

BP314

Sulfamethoxazole, British Pharmacopoeia (BP) Reference Standard

PHR2577

Sulfamethoxazole Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2578

Sulfamethoxazole Impurity A

Pictogrammes

Health hazardEnvironment
GHS08,GHS09

Mention d'avertissement

Warning

Mentions de danger

H361fd,H411

Classification des risques

Aquatic Chronic 2 - Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Raquel González et al.
PLoS medicine, 11(9), e1001735-e1001735 (2014-09-24)
Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women taking daily cotrimoxazole prophylaxis (CTXp) because of potential added risk of adverse effects associated with
R E Levitz et al.
Annals of internal medicine, 100(6), 881-890 (1984-06-01)
Trimethoprim-sulfamethoxazole has excellent microbiologic activity against most pathogens that produce meningitis; both components of this drug have high penetration into tissues, including the cerebrospinal fluid. Clinical experience shows that trimethoprim-sulfamethoxazole may be beneficial in the treatment of gram-negative bacillary meningitis
Co-trimoxazole (trimethoprim-sulfamethoxazole): an updated review of its antibacterial activity and clinical efficacy.
G P Wormser et al.
Drugs, 24(6), 459-518 (1982-12-01)
Jih-Tay Hsu et al.
Journal of hazardous materials, 277, 34-43 (2014-03-19)
Antibiotics are commonly used in swine feed to treat and prevent disease, as well as to promote growth. Antibiotics released into the environment via wastewater could accelerate the emergence of antibiotic-resistant bacteria and resistance genes in the surrounding environment. In
D H Lawson et al.
Reviews of infectious diseases, 4(2), 429-433 (1982-03-01)
A comprehensive review is presented of the world literature on adverse reactions to trimethoprim-sulfamethoxazole (TMP-SMZ) since its first use in 1968, when concern was expressed about possible hematologic toxicity. Serious toxicity is a rare event, but when it occurs severe
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