1272000

5-Fluorocytosine

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : 5-Fluorocytosine, 4-amino-5-fluoro-2(1H)-pyrimidinone, Flucytosine
• Formule empirique (notation de Hill): C₄H₄FN₃O
• Numéro CAS: 2022-85-7
• Poids moléculaire : 129.09
• Beilstein: 127285
• Numéro MDL: MFCD00006035
• Code UNSPSC : 41116107
• ID de substance PubChem : 329749852
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: flucytosine
• Fabricant/nom de marque: USP
• Pf: 298-300 °C (dec.) (lit.)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: NC1=NC(=O)NC=C1F
• InChI: 1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)
• Clé InChI: XRECTZIEBJDKEO-UHFFFAOYSA-N

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Flucytosine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Flucytosine Capsules
• Flucytosine Compounded Oral Suspension

Actions biochimiques/physiologiques

Nucleoside analog that has antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Warning
• Mentions de danger: H361
• Conseils de prudence: P280
• Classification des risques: Repr. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable