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1173100

USP

Desmethoxycurcumin

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione

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About This Item

Formule empirique (notation de Hill):
C20H18O5
Numéro CAS:
22608-11-3
Poids moléculaire :
338.35
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

curcumin

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

InChI

1S/C20H18O5/c1-25-20-12-15(6-11-19(20)24)5-10-18(23)13-17(22)9-4-14-2-7-16(21)8-3-14/h2-12,21,24H,13H2,1H3/b9-4+,10-5+

Clé InChI

HJTVQHVGMGKONQ-LUZURFALSA-N

Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Desmethoxycurcumin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Curcuminoids Tablets
  • Curcuminoids
  • Powdered Turmeric Extract
  • Powdered Turmeric
  • Turmeric

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Tetrahydrocurcumin analytical standard

Supelco

50202

Tetrahydrocurcumin

Tetrahydrocurcumin ≥96% (HPLC)

Sigma-Aldrich

SMB00370

Tetrahydrocurcumin

Curcumin from Curcuma longa (Turmeric), powder

Sigma-Aldrich

C1386

Curcumin

Curcumin ≥94% (curcuminoid content), ≥80% (Curcumin)

Sigma-Aldrich

C7727

Curcumin

Curcumin primary reference standard

00280590

Curcumin

Curcumin for synthesis

Sigma-Aldrich

8.20354

Curcumin

Mei-Chun Kou et al.
Molecular nutrition & food research, 57(9), 1598-1610 (2013-02-07)
Curcumin (CUR), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC) have been demonstrated as having antioxidant, anticarcinogenic, and hypocholesterolemic activities. We report the diverse antiatherogenic effects and mechanisms of curcuminoids. We found that CUR was the most potent antioxidant against copper-mediated LDL oxidation
Kun Wang et al.
Current drug metabolism, 14(7), 791-806 (2013-08-14)
Curcuminoids are safe natural yellow pigments used as food coloring agents and traditional drugs with a variety of biological functions such as antitumor, anti-inflammatory and antioxidant activities. Poor oral bioavailability and the low plasma concentration of curcuminoids limited their clinical
Yanyu Xiao et al.
Journal of agricultural and food chemistry, 61(15), 3654-3660 (2013-03-05)
Curcuminoid, a dietary polyphenolic compound, has poor water solubility and low bioavailability following oral administration. The aim of this study was to develop a formulation of curcuminoid-loaded microemulsion (Cur-ME) to improve its oral bioavailability. The optimized Cur-ME formulation was prepared
Jian-Lan Jiang et al.
Chemical biology & drug design, 81(5), 650-657 (2013-01-29)
Traditionally, active compounds were discovered from natural product extracts by bioassay-guided fractionation, which was with high cost and low efficiency. A well-trained support vector regression model based on mean impact value was used to identify lead active compounds on inhibiting
Ming-Jyh Sheu et al.
Molecular nutrition & food research, 57(9), 1586-1597 (2013-03-23)
Curcumin has been shown to affect platelet-derived growth factor (PDGF)- and tumor necrosis factor (TNF)-α-elicited vascular smooth muscle cell (VSMC) migration and inhibit neointima formation following vascular injury. However, whether two other curcuminoids isolated from Curcuma longa, demethoxycurcumin (DMC) and
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