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568533-U

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Discovery® HS C18 (5 µm) HPLC Columns

L × I.D. 25 cm × 10 mm, HPLC Column

Synonyme(s) :

Discovery RP18 HPLC Column

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About This Item

Code UNSPSC :
41115700
eCl@ss :
32110501
Nomenclature NACRES :
SB.52

product name

Colonne HPLC Discovery® HS C18, 5 μm particle size, L × I.D. 25 cm × 10 mm

Matériaux

stainless steel column

Agence

suitable for USP L1

Gamme de produits

Discovery®

Caractéristiques

endcapped

Fabricant/nom de marque

Discovery®

Conditionnement

1 ea of

Ampleur du marquage

20% Carbon loading

Paramètres

≤70 °C temp. range
400 bar pressure (5801 psi)

Technique(s)

HPLC: suitable

L × D.I.

25 cm × 10 mm

Superficie

300 m2/g

Couverture de surface

3.2 μmol/m2

Impuretés

<10 ppm metals

Matrice

silica gel, high purity, spherical particle platform
fully porous particle

Groupe de la matrice active

C18 (octadecyl) phase

Taille des particules

5 μm

Dimension de pores

120 Å

operating pH range

2-8

Application(s)

food and beverages

Technique de séparation

reversed phase

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Description générale

Discovery® HS C18 HPLC column is specifically developed for pharmaceutical analyses and purification.

Application


  • Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping: This research utilizes the Discovery® HS C18 HPLC column for its superior selectivity and sensitivity in pharmacogenetic studies, providing vital data for personalized medicine approaches in drug metabolism (Abouir et al., 2024).

  • A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies: This study highlights the effectiveness of the Discovery® HS C18 column in the rapid and accurate analysis of molnupiravir, emphasizing its role in supporting fast-paced pharmaceutical research and development (Reçber et al., 2022).

  • Sensitive Analysis of Idarubicin in Human Urine and Plasma by Liquid Chromatography with Fluorescence Detection: This application underlines the Discovery® HS C18 column′s high sensitivity and robustness in clinical diagnostics, crucial for monitoring therapeutic drugs and their metabolites in complex biological matrices (Maliszewska et al., 2020).

Caractéristiques et avantages

  • Stables, faible relargage pour applications LC-MS
  • Changement d′échelle de l′analytique à la préparative
  • Haute stabilité pour assurer une excellente reproductibilité d′injection à injection et de lot à lot
  • Hydrophobicité plus élevée pour une meilleure résolution des analytes difficiles
   

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Informations légales

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificats d'analyse (COA)

Lot/Batch Number
281713-01
281609-01
281606-01
281602-01
281353-01

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Abad Khan et al.
Talanta, 84(3), 789-801 (2011-04-13)
A new, simple, economical and validated high-performance liquid chromatography linked with electrochemical detector (HPLC-ECD) method has been developed and optimized for different experimental parameters to analyze the most common monothiols and disulfide (cystine, cysteine, homocysteine, methionine, reduced (GSH) and oxidized
Awantika Singh et al.
Rapid communications in mass spectrometry : RCM, 29(6), 485-496 (2015-07-15)
Adhatoda beddomei and Adhatoda vasica are popular Ayurvedic medicinal plants in India, belonging to the family Acanthaceae. Tricyclic quinazoline alkaloids are found to be the most abundant in these plants which are responsible for broad-spectrum medicinal properties. This study aims
Swati Jaiswal et al.
Journal of chromatographic science, 55(6), 617-624 (2017-03-24)
Tuberculosis (TB) with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome represents the most common infectious diseases worldwide. Anti-TB drugs are used concurrently with antiretroviral drug for treatment of TB-HIV co-morbidities. Due to lower risk of interaction with protease inhibitors, rifabutin is
Ismail Khan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1033-1034, 261-270 (2016-09-07)
A simple, economical, fast, and sensitive RP-HPLC-UV method has been developed for the simultaneous quantification of Sorafenib and paclitaxel in biological samples and formulations using piroxicam as an internal standard. The experimental conditions were optimized and method was validated according
Lucie Zelena et al.
Journal of pharmaceutical and biomedical analysis, 137, 70-77 (2017-01-17)
Efavirenz is an antiretroviral drug used in the treatment of HIV-positive patients. A simple, fast and sensitive high-performance liquid chromatography (HPLC) method was developed in order to determine efavirenz in three types of samples provided from pharmacokinetic studies. The analysis
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Protocoles

GC Analysis of a Grain Fatty Acid Methyl Ester (FAME) Mix on SP™-2560

-11-eicosenoate; Methyl elaidate; Methyl linoleate; Methyl myristate; Methyl myristoleate; Methyl palmitate; Methyl palmitoleate; Methyl oleate; Methyl pentadecanoate; Methyl tridecanoate; Methyl behenate; Methyl caprylate; Methyl erucate; Methyl heptadecanoate; Methyl arachidate

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

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