SAB4200197

Anti-Periostin antibody,Mouse monoclonal

clone 47, purified from hybridoma cell culture

• Synonyme(s) : Periostin Antibody, Periostin Antibody - Monoclonal Anti-Periostin antibody produced in mouse, Anti-OSF2, Anti-Osteoblast specific factor 2, Anti-PDLPOSTN, Anti-POSTN
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Conjugué: unconjugated
• Forme d'anticorps: purified from hybridoma cell culture
• Type de produit anticorps: primary antibodies
• Clone: 47, monoclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen ~88 kDa
• Espèces réactives: human
• Concentration: ~1.0 mg/mL
• Technique(s): western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin
• Isotype: IgG1
• Numéro d'accès UniProt: Q15063
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... POSTN(10631)

Description

Description générale

Periostin (POSTN) is also known as osteoblast-specific factor-2. It is a 90 kDa protein expressed in the extracellular matrix and bones. POSTN is an adhesive glycoprotein. The gene encoding this protein is localized on human chromosome 13q13.3.

Immunogène

human Periostin recombinant protein. The human protein shares 87% homology with the mouse protein.

Application

Monoclonal Anti-Periostin antibody produced in mouse has been used to develop a periostin imaging PET probe.

Actions biochimiques/physiologiques

Periostin (POSTN) has a role in the differentiation and cell adhesion of osteogenic cells. It functions as a biomarker of T-helper cells type 2-mediated inflammatory diseases. The protein has been associated with various cancers. POSTN is involved in epithelial-mesenchymal transition and extracellular matrix degradation.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable