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Key Documents

SAB2500068

Sigma-Aldrich

Anti-Androgen Receptor antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-AIS, Anti-AR, Anti-Dihydrotestosterone receptor, Anti-KD, Anti-TFM

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

goat

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

human

Technique(s)

ChIP: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... AR(367)

Description générale

Androgen receptor (AR) is a nuclear transcription factor. It belongs to the steroid hormone receptor superfamily. AR gene is located on human chromosome Xq12. AR is present in endothelial and vascular smooth muscle cells.

Immunogène

Peptide with sequence EVQLGLGRVYPRPPSC from the N Terminus of the protein sequence according to NP_000035.2.

Actions biochimiques/physiologiques

Androgens like testosterone and 5α-dihydrotestosterone are required for the progression, growth, differentiation and maintenance of organ structure of the prostate. It plays a major role in normal and malignant breast tissue.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Mention d'avertissement

Warning

Mentions de danger

Conseils de prudence

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Androgen receptor expression on circulating tumor cells in metastatic breast cancer.
Fujii T, et al.
PLoS ONE, 12(9), e0185231-e0185231 (2016)
The CAG repeat polymorphism in the AR gene affects high density lipoprotein cholesterol and arterial vasoreactivity.
Zitzmann M, et al.
The Journal of Clinical Endocrinology and Metabolism, 86(10), 4867-4873 (2001)
FISH analysis of gene aberrations (MYC, CCND1, ERBB2, RB, and AR) in advanced prostatic carcinomas before and after androgen deprivation therapy.
Kaltz-Wittmer C, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 80(9), 1455?1464-1455?1464 (2000)
Melissa A Babcook et al.
Molecular cancer therapeutics, 13(10), 2288-2302 (2014-08-15)
Docetaxel chemotherapy remains a standard of care for metastatic castration-resistant prostate cancer (CRPC). Docetaxel modestly increases survival, yet results in frequent occurrence of side effects and resistant disease. An alternate chemotherapy with greater efficacy and minimal side effects is needed.

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