Accéder au contenu
Merck
Toutes les photos(1)

Key Documents

RAB0695

Sigma-Aldrich

Human IL21 / Interleukin-21 ELISA Kit

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32

Espèces réactives

human

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable

Entrée

sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 110 pg/mL
standard curve range: 125-8000 pg/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... IL21(59067)

Description générale

Interleukin-21 (IL-21) is a pleiotropic cytokine. It belongs to the common γ-chain cytokines with broad pleiotropic actions. This gene is located on human chromosome 4q27.

Application

Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Actions biochimiques/physiologiques

Interleukin-21 (IL-21) regulates chronic viral infection, thereby plays a major role for immune responses in a mouse model of HBV (hepatitis B virus) infection. This gene is linked to celiac disease, rheumatoid arthritis (RA), type 1 diabetes mellitus (type 1 DM) and psoriatic arthritis. IL-21 has the ability to promote maturation and increase the cytotoxicity of CD8+ T cells and natural killer (NK) cells.
The antibody pair provided in this kit recognizes Human Interleukin-21.

Autres remarques

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Composants de kit également disponibles séparément

Réf. du produit
Description
FDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)FDS
  • RABSTOP3ELISA Stop Solution (Item I)FDS
  • RABWASH420X Wash Buffer (Item B)FDS

Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Warning

Mentions de danger

H290

Conseils de prudence

P234 - P390

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Yong Liu et al.
International immunopharmacology, 22(1), 98-106 (2014-07-01)
The frequency of different subsets of CD4(+)CXCR5(+) TFH cells and serum cytokine levels were analyzed in a total of 14 patients with newly diagnosed hepatitis B virus-associated membranous nephropathy (HBV-MN), 12 individuals with immune-tolerant HBV infection (HBV-IT) and 12 healthy
Yolanda P Alemán-García et al.
Journal of immunology research, 2021, 6630715-6630715 (2021-03-26)
Systemic lupus erythematosus is characterized by high levels of IgG class autoantibodies that contribute to the pathophysiology of the disease. The formation of these autoantibodies occurs in the germinal centers, where there is cooperation between follicular T helper cells (TFH)
Association of the autoimmunity locus 4q27 with juvenile idiopathic arthritis
Albers HM, et al.
Arthritis and Rheumatism, 60(3), 60(3)-60(3) (2009)
Induction of IL-21 in Peripheral T Follicular Helper cells is Indicator of Influenza Vaccine Response in Previously Vaccinated HIV-Infected Pediatric Cohort
de Armas LR, et al.
Journal of Immunology (2017)
Sheng Cheng et al.
International journal of clinical and experimental medicine, 7(10), 3202-3208 (2014-11-25)
Asthma is characterized by airway inflammation, mucus overproduction, and airway hyperreactivity. Cytokines, especially T helper 2-derived cytokines interleukin (IL)-4, IL-5, and IL-13, are involved in the pathogenesis of asthma. IL-21 has a variety of effects on the immune system. However
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique