Toutes les photos(2)

Principaux documents

PLA0248

Rabbit anti-BAP1 Antibody, Affinity Purified

Name: Rabbit anti-BAP1 Antibody, Affinity Purified
Brand: SIGMA

Powered by Bethyl Laboratories, Inc.

Synonyme(s) :

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase), BRCA1-associated protein 1, HUCEP-13, KIAA0272, UCHL2, cerebral protein 6, cerebral protein-13, hucep-6, ubiquitin carboxy-terminal hydrolase

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme

Toutes les photos(2)

About This Item

Code UNSPSC :

12352203

Nomenclature NACRES :

NA.41

Produits recommandés

Slide 1 of 1

1 of 1

Sigma-Aldrich

ABF191

Anti-FcRn (FCGRT)

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

affinity purified immunoglobulin

Type de produit anticorps

primary antibodies

Qualité

Espèces réactives

human

Technique(s)

immunoprecipitation (IP): 5-10 μg/mg
western blot: 1:2,000- 1:10,000

Numéro d'accès

NP_004647.1

Numéro d'accès UniProt

Q92560

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

rabbit ... BAP1(8314)

Immunogène

The epitope recognized by PLA0248 maps to a region between residue 679 and 729 of human BRCA1-associated protein 1 using the numbering given in entry NP_004647.1 (GeneID 8314).

Forme physique

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Autres remarques

BRCA1-associated protein 1 (BAP1) functions as a C-terminal ubiquitin hydrolase and may be involved in the transduction of signals in the BRCA1 pathway. BAP1 is also implicated to be a tumor suppressor as defects in BAP1 are found in non-small cell lung cancer cell lines.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Vous ne trouvez pas le bon produit ?

Essayez notre Outil de sélection de produits.

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Inference on germline BAP1 mutations and asbestos exposure from the analysis of familial and sporadic mesothelioma in a high-risk area.

Marta Betti et al.

Genes, chromosomes & cancer, 54(1), 51-62 (2014-09-19)

Inherited loss-of-function mutations in the BAP1 oncosuppressor gene are responsible for an inherited syndrome with predisposition to malignant mesothelioma (MM), uveal and keratinocytic melanoma, and other malignancies. Germline mutations that were inherited in an autosomal dominant fashion were identified in

Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesis.

Han-Sae Lee et al.

Nature communications, 5, 5128-5128 (2014-10-07)

The INO80 chromatin-remodelling complex has been implicated in DNA replication during stress in yeast. However, its role in normal DNA replication and its underlying mechanisms remain unclear. Here, we show that INO80 binds to replication forks and promotes fork progression

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique