N3786
α(2→3,6,8,9) Neuraminidase from Arthrobacter ureafaciens
Proteomics Grade, suitable for MALDI-TOF MS
Synonyme(s) :
Neuraminidase from Arthrobacter ureafaciens, Acyl-neuraminyl Hydrolase, Sialidase
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About This Item
Produits recommandés
Forme
lyophilized powder
Niveau de qualité
Qualité
Proteomics Grade
Activité spécifique
≥25 U/vial
Adéquation
suitable for MALDI-TOF MS
Température de stockage
2-8°C
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Application
Neuraminidase is an important deglycosylation enzyme capable of cleaving all non-reducing unbranched N-acetylneuraminic and N-glycolylneuraminic acid residues by hydrolysis of α(2→6), α(2→3), α(2→8), and α(2→9) linkages (affinity in the order given). Branched sialic acids may also be cleaved with the use of high concentrations of enzyme and prolonged incubations. Desialylated glycoproteins may then be further characterized by treatment with various exoglycosidases resulting in partial or complete O-deglycosylation. SDS-PAGE and MALDI-TOF MS are typically utilized in purification, structural analysis, and sequencing process. These techniques also remove heterogeneity and charge from the glycoprotein.
Conditionnement
Provided with 5× concentrate reaction buffer.
Qualité
The buffer solution has been specifically formulated to assure maximum enzyme stability and assay sensitivity.
Définition de l'unité
One unit will release 1 nmole of 4-methylumbelliferone from 2-(4-methylumbelliferyl) α-D-N-acetylneuraminic acid per minute at pH 5.5 at 37° C.
Forme physique
Lyophilized powder
Composants de kit également disponibles séparément
Réf. du produit
Description
FDS
- N3536Neuraminidase 5X Reaction Buffer 1.5 mLFDS
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Resp. Sens. 1
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Articles
Glycan Sequencing Using Exoglycosidases
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