MAK184
Succinate Colorimetric Assay Kit
Sufficient for 100 Colorimetric tests
Synonyme(s) :
Succinic Acid Assay Kit
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About This Item
Produits recommandés
Application(s)
cosmetics
food and beverages
Méthode de détection
colorimetric
Maladie(s) pertinente(s)
cardiovascular diseases; immunological diseases
Température de stockage
−20°C
Description générale
Succinate (succinic acid) is a citric acid cycle intermediate and functions in the transport of electrons to the mitochondrial electron transport chain. It also functions in innate immune signaling and induces IL-1β production during inflammation. Succinates have been often used for the treatment of hypertension. Succinate measurements can be useful for studying its metabolic, immunological, and therapeutic activities.
Application
Succinate Colorimetric Assay Kit has been used to measure the concentration of succinate.
Adéquation
Suitable for the detection of succinate in a variety of samples such as cell and tissue culture supernatants and in liquid samples such as wine.
Principe
The Succinate Colorimetric Assay Kit is a highly sensitive assay for determining succinate levels (ranging from 2-10 nmole/well) in a variety of samples. Succinate concentration is determined by a coupled enzyme reaction, which results in a colorimetric (450 nm) product proportional to the succinate present.
Composants de kit seuls
Réf. du produit
Description
- Succinate Assay Buffer
- Succinate Converter
- Succinate Enzyme Mix
- Succinate Substrate Mix
- Succinate Developer
- Succinate Standard
Mention d'avertissement
Danger
Mentions de danger
Classification des risques
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
Code de la classe de stockage
8A - Combustible corrosive hazardous materials
Certificats d'analyse (COA)
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Electron Transport and Oxidative Phosphorylation
Lodish H, et al.
Molecular Cell Biology (2000)
Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis.
Tretter L, et al.
Biochimica et Biophysica Acta - Bioenergetics, 1857(8), 1086-1101 (2016)
VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism.
Li J, et al.
Nature Communications, 8(1), 1322-1322 (2017)
Metoprolol succinate extended release/hydrochlorothiazide combination tablets.
Hainer JW and Jennifer S
Vascular Health, 3(3), 279-279 (2007)
DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism.
Shen J, et al.
JCI insight, 2(12) (2017)
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