L8000

L-Leucine

≥98% (HPLC), suitable for ligand binding assays

• Synonyme(s) : (S)-2-Amino-4-methylpentanoic acid
• Formule linéaire : (CH₃)₂CHCH₂CH(NH₂)CO₂H
• Numéro CAS: 61-90-5
• Poids moléculaire : 131.17
• Numéro Beilstein : 1721722
• Numéro CE : 200-522-0
• Numéro MDL: MFCD00002617
• Code UNSPSC : 12352209
• eCl@ss : 32160406
• ID de substance PubChem : 24896488
• Nomenclature NACRES : NA.26

Propriétés

• product name: L-Leucine, reagent grade, ≥98% (HPLC)
• Qualité: reagent grade
• Pureté: ≥98% (HPLC)
• Forme: powder
• Technique(s): ligand binding assay: suitable
• Impuretés: isoleucine and methionine, essentially free
• Couleur: white to off-white
• Pf: >300 °C (lit.)
• Application(s): peptide synthesis
• Chaîne SMILES: CC(C)C[C@H](N)C(O)=O
• InChI: 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
• Clé InChI: ROHFNLRQFUQHCH-YFKPBYRVSA-N

Description

Application

L-Leucine has been used as an agonist of mechanistic target of rapamycin (mTOR) to determine whether AMPK/mTOR pathway is involved in berberine-mediated autophagy in J774A.1 cells. It has also been used for the selection of transformed cells.

Actions biochimiques/physiologiques

Leucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)