H8909

HBcAg core human

~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli

• Synonyme(s) : Hepatitis B virus core antigen
• Numéro MDL: MFCD02264925
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Produit recombinant: expressed in E. coli
• Niveau de qualité: 200
• Essai: ≥95% (SDS-PAGE)
• Poids mol.: 18 kDa
• Concentration: ~1 mg/mL
• Numéro d'accès UniProt: G9G988
• Température de stockage: −20°C
• Informations sur le gène: hepatitis B virus ... HBVgp4(944568) ; human ... HBVgp4(944568)

Description

Description générale

amino acids 1-183 of HBV core antigen.

Actions biochimiques/physiologiques

HBcAg core human is a capsid protein of hepatitis B virus (HBV). It acts as a viral factor for HBV clearance. HBcAg is implicated in viral replication.

Hepatitis B virus core antigen (HBcAg) is a positive control for human HBV antibodies.In humans with chronic HBV (hepatitis B virus) infection, cytotoxic effects of blood T lymphocytes can be suppressed by incubating cells with antibodies against hepatitis B core antigen (HBcAg). The antigen can also work as a T-cell independent antigen in athymic mice. However, it is an efficient immunogen, resulting in T-cell activation and increased anti-HBc levels. High cytoplasmic/membranous expression of HBcAg is associated with increased liver inflammation.

Forme physique

Solution in 50% glycerol, 7.5 mM phosphate buffer, pH 7.2, 75 mM NaCl.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable