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Key Documents

SAB4700767

Sigma-Aldrich

Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse

clone HB5, purified immunoglobulin, buffered aqueous solution

Synonyme(s) :

Hbsag Antibody, Hbsag Antibody - Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Conjugué

unconjugated

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

HB5, monoclonal

Forme

buffered aqueous solution

Espèces réactives

hepatitis B virus

Concentration

1 mg/mL

Technique(s)

ELISA: suitable
immunocytochemistry: suitable

Isotype

IgG2a

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Description générale

HBsAg is the surface antigen of HBV (hepatitis B virus). It is secreted in the form of pleomorphic particles, mostly spherical and partly filamentous. HBV is usually spread due to percutaneous or mucosal exposure to infected blood and other body fluids.
The antibody HB5 recognizes following Hepatitis B virus (HBV) subtypes: ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-. Hepatitis B surface antigen (HBsAg) is a marker of infectivity.
Specificity of the antibody HB5 was verified by ELISA on panel of virus subtypes identified on International Workshop on HBsAg Subtypes (Paris, April 1975). The antibody HB5 does not cross-block with the antibody HB3.

Immunogène

Purified HbsAg from human plasma.

Application

Monoclonal Anti-HBV antigen HBsAg antibody has been used in quantitative assays.

Actions biochimiques/physiologiques

HBsAg acts as a clinical marker and helps to specify acute or chronic infection. Presence of HBsAg indicates HBV infection. Overexpression of HBsAg is seen in infected hepatocytes.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Hepatitis B and D Protocols (2004)
Palashpriya Das et al.
World journal of hepatology, 12(10), 775-791 (2020-11-18)
The recent rise in the incidence of hepatitis B virus (HBV) infections in a densely populated city of eastern India ("mixing vessel" of people of varied socio-economic and immune status) prompted this study. Applying saliva on fingers for enumerating bank
Establishment of magnetic microparticles-assisted time-resolved fluoroimmunoassay for determinating biomarker models in human serum.
Ren ZQ, et al.
PLoS ONE, 10(6), e0130481-e0130481 (2015)
Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity.
Ott JJ, et al.
Vaccine, 30(12), 2212-2219 (2012)
Zhi-Qi Ren et al.
PloS one, 10(6), e0130481-e0130481 (2015-06-24)
In order to early screen and detect suspected biomarkers from pathogens and the human body itself, tracers or reaction strategies that can act as signal enhancers have been proposed forth at purpose. In this paper, we discussed the applicability of

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