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Key Documents

D8517

Sigma-Aldrich

Iron–Dextran

95-105 mg/mL (Iron content), solution

Synonyme(s) :

Ferric hydroxide dextran complex

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About This Item

Numéro CAS:
9004-66-4
Numéro MDL:
MFCD00081553
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25

Source biologique

synthetic

Niveau de qualité

200

Stérilité

aseptically filled

Pureté

95-105 mg/mL (Iron content)

Forme

solution

Contient

0.5% phenol as preservative

Composition

Iron, ~100 mg/mL

Couleur

brown

Plage de pH utile

4 - 6.5

Température de stockage

room temp

InChI

1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)

Clé InChI

MVZXTUSAYBWAAM-UHFFFAOYSA-N

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Application

Iron-Dextran (ferric hydroxide dextran complex) may be used as an intravenous iron delivery preparation. Iron-Dextran may be used to induce iron-overload to study its effects and preventative measures.

Autres remarques

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Danger

Mentions de danger

H317,H350

Classification des risques

Carc. 1B - Skin Sens. 1

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Yong Won Cho et al.
Sleep medicine, 14(3), 274-277 (2013-01-22)
Various techniques used to assess brain iron concentrations have demonstrated the presence of low iron stores in patients with restless legs syndrome (RLS). Previous open-label and randomized studies generally support the value of iron treatment for RLS symptoms. Only one
John C Wood et al.
Magnetic resonance in medicine, 60(1), 82-89 (2008-06-27)
MRI is gaining increasing importance for the noninvasive quantification of organ iron burden. Since transverse relaxation rates depend on iron distribution as well as iron concentration, physiologic and pharmacologic processes that alter iron distribution could change MRI calibration curves. This
Natacha E Piloni et al.
Toxicology, 314(1), 174-182 (2013-10-15)
An in vivo model in rat was developed by intraperitoneally administration of Fe-dextran to study oxidative stress triggered by Fe-overload in rat brain. Total Fe levels, as well as the labile iron pool (LIP) concentration, in brain from rats subjected
Yonggang Gao et al.
Journal of ethnopharmacology, 145(1), 254-260 (2012-11-14)
Danshen (Salvia miltiorrhiza) has been widely prescribed in traditional folk medicine for treatment of hepatic and cardiovascular diseases in China and other Asian countries for several hundred years. Sixty male mice were randomly divided into five groups: control, iron overload
Raymond J Bergeron et al.
Journal of medicinal chemistry, 51(13), 3913-3923 (2008-06-07)
A series of iron-clearing efficiencies (ICEs), ferrokinetics, and toxicity studies for ( S)-2-(2,4-dihydroxyphenyl)-4,5-dihydro-4-methyl-4-thiazolecarboxylic acid (deferitrin, 1), ( S)-4,5-dihydro-2-[2-hydroxy-4-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylic acid ( 2), and (S)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylic acid ( 3) are reported. The ICEs in rodents are shown to be dose-dependent and saturable for
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