C8180
Cholera Toxin A Subunit from Vibrio cholerae
lyophilized powder
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About This Item
Produits recommandés
Forme
lyophilized powder
Niveau de qualité
Composition
Protein, ~5% Lowry
Disponibilité
not available in Japan
Impuretés
≤0.5% Cholera toxin B subunit (SDS-PAGE)
Température de stockage
2-8°C
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Description générale
Cholera Toxin (CT) is secreted by Vibrio cholerae. CT upregulates cell surface molecules, such as co-stimulatory molecules and chemokine receptors in antigen presenting cells(APCs), murine and human dendritic cells (DCs). It enhances the secretion of interleukin 1 (IL-1) from macrophages and stimulates their APC function. CT also functions as an immunomodulator.
Application
Cholera Toxin A Subunit from Vibrio cholerae has been used as a specific probe for trimeric G proteins in membrane motility assays.
Actions biochimiques/physiologiques
Catalyzes ADP-ribosylation of the α-subunit of G proteins, reducing GTPase activity and activating the α-subunit; also catalyzes ADP-ribosylation of cell membrane adenylyl cyclase
Forme physique
Lyophilized powder containing Tris buffer salts, sodium chloride, sodium azide and sodium EDTA
Reconstitution
When reconstituted with 1 mL of water, the solution will contain 0.05 M Tris buffer salts, pH 7.5, 0.2 M NaCl, 0.003 M NaN3, and 0.001 M sodium EDTA. Store reconstituted solutions in the refrigerator.
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Acute Tox. 4 Inhalation - Aquatic Chronic 3
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Les clients ont également consulté
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