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B1557

Sigma-Aldrich

Hyaluronan biotin sodium salt

≥97%, soluble powder

Synonyme(s) :

Hyaluronic acid biotin

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About This Item

Numéro MDL:
MFCD03457192
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25

Niveau de qualité

100

Pureté

≥97%

Forme

soluble powder

Poids mol.

≥700 kDa

Perte

≤5% loss on drying

Couleur

white to tan

Température de stockage

2-8°C

Catégories apparentées

Application

Hyaluronan biotin (HA-biotin) may be used as a specific bioaffinity probe to detect HA-binding proteins (hyaladherins), HA-receptors and HA-binding components in tissues and cells. Hyaluronan biotin may be used in the development of affinity binding systems for the immobilization and purification of hyaladherins. HA-biotin may be used in hydrogel development and for drug targeting.
Highly sensitive probe for detecting nanogram levels of hyaluronan binding proteins (hyaladherins).

Autres remarques

From cocks comb or fermentation.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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P Auvinen et al.
The American journal of pathology, 156(2), 529-536 (2000-02-10)
Hyaluronan (HA) is an extracellular matrix polysaccharide that promotes cell migration through its cell surface receptors and by effecting changes in the physical environment. HA expression is frequently increased in malignant tumors, whereas its association with the invasive potential and
T Pouyani et al.
Bioconjugate chemistry, 5(4), 370-372 (1994-07-01)
Hyaluronic acid (HA) is a linear polysaccharide composed of repeating disaccharide units of D-glucuronic acid (GlcUA) and N-acetyl-D-glucosamine (GlcNAc). Hyaluronate plays an important role in many biological processes as mediated by its interactions with a number of HA-binding proteins (the
D Liu et al.
Frontiers in bioscience : a journal and virtual library, 3, d631-d636 (1998-06-23)
CD44 is a cell surface glycoprotein present on many cell types. Many CD44 isoforms have been identified. All CD44 isoforms utilize identical transmembrane and cytoplasmic domains. The hematopoietic form of CD44 (CD44H) is the major CD44 protein present on normal
James Melrose et al.
Methods in molecular medicine, 101, 65-78 (2004-08-10)
Hyaluronan (HA) binding proteins (HABPs) were localized in cartilaginous ovine tissues (articular cartilage, intervertebral disc) using a biotinylated HA (bHA) oligosaccharide bioaffinity probe. The bHA oligosaccharide probe was prepared by partial digestion of HA with ovine testicular hyaluronidase, and the
Yuan Cui et al.
Applied biochemistry and biotechnology, 169(1), 239-249 (2012-11-28)
Hyaluronic acid is a naturally ionic polysaccharide with cancer cell selectivity. It is an ideal candidate material for delivery of anticancer agents. In this study, hyaluronic acid (HA) micro-hydrogel loaded with anticancer drugs was prepared by the biotin-avidin system approach.
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