A9210
Annexin V FITC Conjugate from human placenta
Synonyme(s) :
Annexin V, Calphosbindin I, Lipocortin V, PAP-1
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
About This Item
Code UNSPSC :
41106305
Nomenclature NACRES :
NA.32
Produits recommandés
Forme
buffered aqueous solution
Niveau de qualité
Ampleur du marquage
1-2 mol FITC per mol annexin V
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Température de stockage
2-8°C
Informations sur le gène
human ... ANXA5(308)
Vous recherchez des produits similaires ? Visite Guide de comparaison des produits
Application
For detection of apoptotic cells by flow cytometry or fluorescence microscopy.
Actions biochimiques/physiologiques
Annexins are ubiquitous homologous proteins that bind phospholipids in the presence of calcium. The cellular changes involved in the apoptotic process include loss of phospholipid asymmetry during the early stages. This phenomenon is universal and is not limited to stimulus or to mammalian cells, but also occurs in insect and plant cells. In living cells, phosphatidylserine is transported to the inside of the lipid bilayer by the Mg2+ATP dependent enzyme, aminophospholipid translocase. At the onset of apoptosis, phosphatidylserine becomes translocated to the external surface of the cell membrane. Since the movement of phosphatidylserine from the internal membrane surface to the external surface is an early indicator of apoptosis, annexin V and its conjugates that interact strongly and specifically with phosphatidylserine may be used to detect apoptosis. Annexin V conjugates can be used to detect apoptotic cells significantly earlier than DNA-based assays. Fluorescent dye labeled annexin V have applications in flow cytometry, fluorescence microscopy, and laser scanning cytometry.
Conditionnement
Package size based on protein content
Forme physique
Solution in 50 mM Tris-HCl, pH 7.5, containing 100 mM NaCl.
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Les clients ont également consulté
Carolina Orlando Vaso et al.
Pharmaceutics, 14(5) (2022-05-29)
Histoplasma capsulatum is a fungus that causes histoplasmosis. The increased evolution of microbial resistance and the adverse effects of current antifungals help new drugs to emerge. In this work, fifty-four nitrofurans and indoles were tested against the H. capsulatum EH-315
Li-Min Zhu et al.
Frontiers in oncology, 11, 690878-690878 (2021-07-20)
Feiyanning formula (FYN) is a traditional Chinese medicine (TCM) prescription used for more than 20 years in the treatment of lung cancer. FYN is composed of Astragalus membranaceus, Polygonatum sibiricum, Atractylodes macrocephala, Cornus officinalis, Paris polyphylla, and Polistes olivaceous, etc.
Mahmoud Hasan et al.
Marine drugs, 16(7) (2018-06-27)
Curcumin (diferuloylmethane) is a natural bioactive compound with many health-promoting benefits. However, its poor water solubility and bioavailability has limited curcumin’s biomedical application. In the present study, we encapsulated curcumin into liposomes, formed from natural sources (salmon lecithin), and characterized
Yunqi Zhao et al.
Oncology letters, 20(6), 289-289 (2020-10-09)
Linalool is an unsaturated terpene that can be found in several plants and exhibits various biological activities. The aim of the present study was to investigate the anticancer activity of linalool using the human prostate cancer 22Rv1 cell line. Flow
C Haro et al.
Beneficial microbes, 10(5), 533-541 (2019-04-10)
Streptococcus pneumoniae is able to activate coagulation and induce platelet aggregation, both of which are typical responses to systemic inflammation. The interactions between inflammation and coagulation and between soluble adhesion molecules and endothelial cells are important in the pathogenesis of
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique