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Merck
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Key Documents

A5472

Sigma-Aldrich

Formalin Free Tissue Fixative

greener alternative
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About This Item

Code UNSPSC :
12171500
Nomenclature NACRES :
NA.47

Forme

solution

Caractéristiques du produit alternatif plus écologique

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Couleur

colorless

Densité

1.044 g/cm3

Application(s)

hematology
histology

Autre catégorie plus écologique

Température de stockage

room temp

Application

A formalin-free tissue fixative that is a less toxic alternative to formalin. Performs well with PCR, in-situ hybridization and immunohistological staining.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.

Autres remarques

Alcoholic solution with hydroxylated compounds. The product is ready to use and requires no dilution or preparation.

Pictogrammes

Flame

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Flam. Liq. 3

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

118.0 °F

Point d'éclair (°C)

47.8 °C


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

M E Boon et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 83(6), 261-277 (2008-11-26)
The German, F. Blum, introduced formalin as a fixative in 1893. Formalin rapidly became popular for hardening and preserving gross human and animal specimens. As a result, microscopy for diagnostic pathology by combining paraffin embedding and formalin fixation was developed.
Mee Kum Kim et al.
Journal of Korean medical science, 23(5), 864-869 (2008-10-29)
To compare the stem niche in different culture conditions of limbal epithelial cells, the suspended human limbal epithelial cells (HLECs) were seeded on the 3T3-pretreated plates and the other suspended cells were plated on amniotic membranes (AMs) which were either
Hannelore Kothmaier et al.
Archives of pathology & laboratory medicine, 135(6), 744-752 (2011-06-03)
Formalin-fixed, paraffin-embedded tissue is the routine processing method for diagnostics practiced in pathology departments worldwide. To determine the potential value of non-cross-linking, formalin-free tissue fixation for diagnostics in pathology and proteomic investigations. We tested 3 commercially available, formalin-free tissue fixatives-FineFIX
R Scott Pearsall et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(19), 7082-7087 (2008-05-08)
Diseases that affect the regulation of bone turnover can lead to skeletal fragility and increased fracture risk. Members of the TGF-beta superfamily have been shown to be involved in the regulation of bone mass. Activin A, a TGF-beta signaling ligand

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