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Merck
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Key Documents

A2787

Sigma-Aldrich

N-Acetyl-D-galactosamine–Agarose

saline suspension

Synonyme(s) :

N-Acetyl Galactosamine

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About This Item

Numéro MDL:
MFCD00164853
Code UNSPSC :
23151817
Nomenclature NACRES :
NA.56

Source biologique

plant

Forme

saline suspension

Technique(s)

affinity chromatography: suitable

Matrice

cross-linked 4% beaded agarose

Activation de la matrice

epoxy

Fixation de matrice

6-hydroxy

Espaceur de matrice

12 atoms

Capacité

≥6 mg/mL binding capacity (lectin from Glycine max)

Adéquation

suitable for chromatography

Température de stockage

2-8°C

Application

N-Acetyl-D-galactosamine is an agarose used in affinity chromatography, protein chromatography and in carbohydrate matrices. N-Acetyl-D-galactosamine has been used to study periodontal disease and to facilitate the design of potent small-molecule ice recrystallization inhibitors. N-Acetyl-D-galactosamine has also been used to demonstrate a molecular shuttle between extracellular and cytoplasmic space allows for monitoring of GAG biosynthesis.

Forme physique

Suspension in 0.5 M NaCl containing preservative.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Anna K Balcerzak et al.
Bioorganic & medicinal chemistry letters, 22(4), 1719-1721 (2012-01-24)
The β-d-galactosyl-(1,3)-α-N-acetyl-d-galactosamine disaccharide is present in antifreeze glycoproteins (AFGPs). Analogs of this disaccharide including the β-linked (1,3)-, (1,4)-, and (1,6)-galactosyl-N-acetyl galactosamine and the β-(1,3)-galactosyl-galactoside were synthesized and evaluated for ice recrystallization inhibition (IRI) activity. The results from this study demonstrate
Hiroko Hoshi et al.
Biochimica et biophysica acta, 1820(9), 1391-1398 (2012-01-24)
Cell surface proteoglycans play vital functional roles in various biological processes such as cell proliferation, differentiation, adhesion, inflammation, immune response, sustentation of cartilage tissue and intensity of tissues. We show here that serglycin-like synthetic glycopeptides function efficiently as a molecular
A new histochemical approach for studying sperm cell surfaces.
Ngo, L., et al.
Acta Histochemica, 106(1), 21-28 (2003)
Reynald Tremblay et al.
Transgenic research, 20(2), 345-356 (2010-06-19)
Soybean agglutinin (SBA) is a specific N-acetylgalactosamine-binding plant lectin that can agglutinate a wide variety of cells. SBA has great potential for medical and biotechnology-focused applications, including screening and treatment of breast cancer, isolation of fetal cells from maternal blood
Jining Liu et al.
Xenotransplantation, 10(2), 149-163 (2003-02-18)
Hyperacute organ xenograft rejection can be prevented by removing anti-pig antibodies by extracorporeal absorption prior to transplantation. A novel recombinant absorber of anti-pig antibodies was developed by fusing the cDNA encoding the extracellular part of a mucin-type protein, P-selectin glycoprotein
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