482R-1

p63 (EP174) Rabbit Monoclonal Primary Antibody

• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100; 500
• Conjugué: unconjugated
• Forme d'anticorps: culture supernatant
• Type de produit anticorps: primary antibodies
• Clone: EP174
• Description: For In Vitro Diagnostic Use in Select Regions
• Forme: buffered aqueous solution
• Espèces réactives: human
• Conditionnement: vial of 0.1 mL concentrate (482R-14); vial of 0.1 mL concentrate, Research Use Only (482R-14-RUO); vial of 0.5 mL concentrate (482R-15); vial of 1.0 mL concentrate (482R-16); vial of 1.0 mL concentrate, Research Use Only (482R-16-RUO); vial of 1.0 mL pre-dilute ready-to-use, Research Use Only (482R-17-RUO); vial of 1.0 mL pre-dilute, ready to use (482R-17); vial of 25.0 mL pre-dilute ready-to-use (482R-10); vial of 25.0 mL pre-dilute ready-to-use, Research Use Only (482R-10-RUO); vial of 7.0 mL pre-dilute, ready to use (482R-18); vial of 7.0 mL pre-dilute, ready to use, Research Use Only (482R-18-RUO)
• Fabricant/nom de marque: Cell Marque
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))
• Isotype: IgG
• Contrôle: lung (squamous cell carcinoma), prostate
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Visualisation: nuclear

Description

Description générale

p63 is a transcription factor that regulates many cell activities, including cell proliferation, maintenance, differentiation, adhesion, and apoptosis.¹ It has been found to be a sensitive and specific marker of myoepithelial and basal cell populations in prostate, breast, skin, and salivary gland. Additionally, p63 has also demonstrated immunohistochemical utility in identifying benign and malignant breast lesions.² In prostatic carcinomas, it can also be used to recognize benign glands adjacent to malignant glands.³ p63 can also be used to differentiate adenocarcinoma of the lungs, where it is usually negative, from squamous cell carcinoma, which can be useful for advanced stages of the carcinoma where surgery is no longer an option.⁴

Qualité

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Notes préparatoires

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Autres remarques

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Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2