465R-1

TROP2 (EP431) Rabbit Monoclonal Primary Antibody

• Synonyme(s) : Trophoblast Antigen 2
• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100; 500
• Conjugué: unconjugated
• Forme d'anticorps: culture supernatant
• Type de produit anticorps: primary antibodies
• Clone: EP431, monoclonal
• Description: For In Vitro Diagnostic Use in Select Regions
• Forme: buffered aqueous solution
• Espèces réactives: human
• Conditionnement: vial of 0.1 mL concentrate (465R-14); vial of 0.1 mL concentrate Research Use Only (465R-14-RUO); vial of 0.5 mL concentrate (465R-15); vial of 1.0 mL concentrate (465R-16); vial of 1.0 mL concentrate Research Use Only (465R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (465R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (465R-17); vial of 7.0 mL pre-dilute ready-to-use (465R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (465R-18-RUO)
• Fabricant/nom de marque: Cell Marque^™
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotype: IgG
• Contrôle: papillary carcinoma of thyroid
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Visualisation: cytoplasmic, membranous
• Informations sur le gène: human ... TACSTD2(4070)

Description

Description générale

Trophoblast antigen 2 (TROP2) is a transmembrane glycoprotein that transduces intracellular calcium signals. The overexpression of TROP2 has been linked to tumor progression due to its involvement in the regulation of multiple vital cell processes including migration, proliferation, and invasion. TROP2 exhibits strong, diffuse staining in papillary thyroid carcinoma, while staining in other thyroid lesions, such as follicular thyroid adenomas and carcinomas, is limited to rare, focal, or scattered cells. An increase in TROP2 expression has also been observed in colorectal carcinomas and ovarian serous carcinomas compared to non-neoplastic ovary and colon.

Qualité

IVD

IVD

IVD

RUO

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Notes préparatoires

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Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2