494496

NMP

biotech. grade, ≥99.7%

• Synonyme(s) : 1-méthyl-2-pyrrolidone, N-méthyl-2-pyrrolidone, M-PYROL, NMP
• Formule empirique (notation de Hill): C₅H₉NO
• Numéro CAS: 872-50-4
• Poids moléculaire : 99.13
• Numéro Beilstein : 106420
• Numéro CE : 212-828-1
• Numéro MDL: MFCD00003193
• Code UNSPSC : 12352005
• ID de substance PubChem : 329757456
• Nomenclature NACRES : NA.07

Propriétés

• product name: 1-méthyl-2-pyrrolidinone, biotech. grade, ≥99.7%
• Qualité: biotech. grade
• Niveau de qualité: 100
• Densité de vapeur: 3.4 (vs air)
• Pression de vapeur: 0.29 mmHg ( 20 °C); 0.99 mmHg ( 40 °C)
• Pureté: ≥99.7%
• Forme: liquid
• Température d'inflammation spontanée: 518 °F
• Limite d'explosivité: 9.5 %
• Impuretés: ≤0.005% water; ≤0.01% free amines (CH₃NH₂)
• Couleur: APHA: ≤20
• Indice de réfraction: n20/D 1.47 (lit.)
• pH: 7.7-10.0 (20 °C, 100 g/L)
• Point d'ébullition: 202 °C (lit.); 81-82 °C/10 mmHg (lit.)
• Pf: −24 °C (lit.)
• Solubilité: acetone: miscible(lit.); alcohol: miscible(lit.); chloroform: miscible(lit.); ethyl acetate: miscible(lit.); water: miscible(lit.)
• Densité: 1.028 g/mL at 25 °C (lit.)
• λ: H₂O reference
• Absorption UV: λ: 285 nm A_max: 1.00; λ: 300 nm A_max: 0.50; λ: 325 nm A_max: 0.10; λ: 350-400 nm A_max: 0.01
• Application(s): peptide synthesis
• Chaîne SMILES: CN1CCCC1=O
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
• Clé InChI: SECXISVLQFMRJM-UHFFFAOYSA-N

Description

Description générale

N-Methyl-2-pyrrolidinone (N-methylpyrrolidone, NMP) is a polar cyclic organic solvent. A study on the impact of NMP on Saccharomyces cerevisiae revealed that it induced aneuploidy. Characteristic properties of NMP include low viscosity, excellent dissolving power and enhanced demulsifying property. It is a better alternative to phenol in selectively treating lube feedstock. The behavior of fullerene-C₆₀ in NMP solution has been examined based on electronic absorption and photoluminescence spectral data. A solution of sodium borohydride (NaBH₄) in NMP showed increased reactivity towards debromination of alkyl bromide. The enhanced selectivity of NMP-ethylene glycol solvent mixture for aromatic hydrocarbon extraction has been analyzed by gas chromatography.

Conditionnement

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Informations sur la sécurité

• Pictogrammes: GHS08,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H315,H319,H335,H360D
• Conseils de prudence: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Classification des risques: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 195.8 °F - Pensky-Martens closed cup
• Point d'éclair (°C): 91 °C - Pensky-Martens closed cup