201030

Osmium tetroxide

ReagentPlus^®, 99.8%

• Synonyme(s) : Osmium(VIII)-oxide, ‘Osmic acid’
• Formule linéaire : OsO₄
• Numéro CAS: 20816-12-0
• Poids moléculaire : 254.23
• Numéro CE : 244-058-7
• Numéro MDL: MFCD00011150
• Code UNSPSC : 12352303
• ID de substance PubChem : 329751973
• Nomenclature NACRES : NA.55

Propriétés

• Densité de vapeur: 8.8 (vs air)
• Niveau de qualité: 200
• Pression de vapeur: 7 mmHg ( 20 °C)
• Gamme de produits: ReagentPlus^®
• Pureté: 99.8%
• Forme: crystalline; powder
• Pertinence de la réaction: reagent type: oxidant
• Point d'ébullition: 130 °C (lit.)
• Pf: 39.5-41 °C (lit.)
• Température de stockage: 2-8°C
• Chaîne SMILES: O=[Os](=O)(=O)=O
• InChI: 1S/4O.Os
• Clé InChI: VUVGYHUDAICLFK-UHFFFAOYSA-N

Description

Description générale

Osmium tetroxide (OsO₄) is widely employed as a catalyst in various organic reactions. Stereochemical aspects of the OsO₄ assisted oxidation of allylic alcohols and their derivatives have been reported. Its reaction with olefins has been investigated. It participates as a catalyst for oxidizing fluoroquinolones, via reaction with potassium hexacyanoferrate(III) in alkaline medium. Kinetics of this oxidation reaction was studied.

Application

Osmium tetroxide may be employed as a catalyst for the hydroxylation of sterically hindered olefins.

Osmium tetroxide may be used in the following processes:

• To promote the lactonization of alkenols to lactones.
• To mediate the selective oxidative cleavage of olefins by oxone to form the corresponding ketones or carboxylic acids.
• Dihydroxylation of mono-trans-di, and trisubstituted olefins to form 1,2-diols with high enantioselectivity in the presence of chiral amines.

Widely used oxidizer for visualizing cells in microscopy. Promotes oxidative cleavage of graphene layers in carbon nanotubes creating the possibility of opening ′windows′ in fullerene cages.

Informations légales

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS06,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H310 + H330,H314
• Conseils de prudence: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable