Y0001601

Alfacalcidol for system suitability

European Pharmacopoeia (EP) Reference Standard

• Synonyme(s) : 1α-Hydroxyvitamin D₃, 1α-Hydroxycholecalciferol, Alfacalcidol
• Formule empirique (notation de Hill): C₂₇H₄₄O₂
• Numéro CAS: 41294-56-8
• Poids moléculaire : 400.64
• Numéro MDL: MFCD00868328
• Code UNSPSC : 41116107
• ID de substance PubChem : 329831506
• Nomenclature NACRES : NA.24

Propriétés

• Source biologique: synthetic
• Qualité: pharmaceutical primary standard
• Agence: EP
• Forme: solid
• Fabricant/nom de marque: EDQM
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: −20°C
• Chaîne SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C
• InChI: 1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1
• Clé InChI: OFHCOWSQAMBJIW-AVJTYSNKSA-N
• Informations sur le gène: human ... VDR(7421)

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Synthetic vitamin D₃ analog that is metabolized to 1,25-dihydroxycholecalciferol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H300
• Conseils de prudence: P301 + P330 + P331 + P310
• Classification des risques: Acute Tox. 1 Oral
• Code de la classe de stockage: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable