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T1900000

Triamcinolone acetonide

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

9α-Fluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide, 9α-Fluoro-16α-hydroxyprednisolone 16α,17α-acetonide

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About This Item

Formule empirique (notation de Hill) :
C24H31FO6
Numéro CAS:
76-25-5
Poids moléculaire :
434.50
Numéro MDL:
MFCD00056834
Code UNSPSC :
41116107
ID de substance PubChem :
329826694
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

triamcinolone

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO

InChI

1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

Clé InChI

YNDXUCZADRHECN-JNQJZLCISA-N

Informations sur le gène

human ... NR3C1(2908)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Triamcinolone acetonide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Danger

Mentions de danger

H302,H360

Classification des risques

Acute Tox. 4 Oral - Repr. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Fluocinolone acetonide European Pharmacopoeia (EP) Reference Standard

F0200000

Fluocinolone acetonide

Triamcinolone

Sigma-Aldrich

T6376

Triamcinolone

USP

USP

1679037

Triamcinolone acetonide Related Compound C

Budesonide ≥99%

Sigma-Aldrich

B7777

Budesonide

Hiroshi Kunikata et al.
American journal of ophthalmology, 155(6), 1028-1037 (2013-03-16)
To investigate the role of intravitreal injection of triamcinolone acetonide (IVTA) in preventing photoreceptor apoptosis in eyes with rhegmatogenous retinal detachment (RRD) by measuring cytokine levels in the aqueous humor before and after IVTA. Prospective, nonrandomized, interventional case series. setting:
Jill S Waibel et al.
Lasers in surgery and medicine, 45(3), 135-140 (2013-03-06)
Hypertrophic scars and contractures are common following various types of trauma and procedures despite skilled surgical and wound care. Following ample time for healing and scar maturation, many millions of patients are burdened with persistent symptoms and functional impairments. Cutaneous
Arthur Geltzer et al.
The Cochrane database of systematic reviews, 1(1), CD005022-CD005022 (2013-02-27)
Neovascular age-related macular degeneration (AMD) is associated with rapid vision loss due to choroidal neovascularization (CNV), leakage, and scarring. Steroids have gained attention in their role for the treatment of neovascular AMD for their antiangiogenic and anti-inflammatory properties. This review
Shivani Kasbekar et al.
Journal of cataract and refractive surgery, 39(3), 414-418 (2013-01-23)
To compare the clinical outcomes in patients who had triamcinolone acetate-assisted anterior vitrectomy and patients who had anterior vitrectomy without triamcinolone acetate after phacoemulsification complicated by posterior capsule rupture and vitreous loss. Arrowe Park Hospital, Wirral, United Kingdom. Retrospective consecutive
Brian C Gilger et al.
Investigative ophthalmology & visual science, 54(4), 2483-2492 (2013-03-28)
To evaluate the effect of triamcinolone acetonide (TA) administered into the suprachoroidal space (SCS) using a microneedle and compare it with intravitreal (IVT) TA injections in a porcine model of acute posterior segment inflammation. An IVT injection of balanced salt
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