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PHL82542

Fisetin

phyproof® Reference Substance

Synonyme(s) :

3,3′,4′,7-Tetrahydroxyflavone, 5-Desoxyquercetin, Cotinin, Fiestin, Fietin

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About This Item

Formule empirique (notation de Hill):
C15H10O6
Numéro CAS:
528-48-3
Poids moléculaire :
286.24
Numéro MDL:
MFCD00006829
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

primary reference standard

Gamme de produits

phyproof® Reference Substance

Pureté

≥90.0% (HPLC)

Fabricant/nom de marque

PhytoLab

Application(s)

food and beverages

Format

neat

InChI

1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H

Clé InChI

XHEFDIBZLJXQHF-UHFFFAOYSA-N

Description générale

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

  • Fisetin anti-inflammatory and antioxidative properties: Fisetin reduces inflammation and oxidative stress in deep vein thrombosis, signaling via the MAPK and NRF2 pathways, highlighting its potential as an anti-inflammatory agent and its importance in managing thrombotic disorders (Liu and Lu, 2024).
  • Fisetin in drug delivery system enhancement: A mechanochemical method improves fisetin′s solubility and biological activity, suggesting its utility in creating effective drug delivery systems that enhance the therapeutic effects of fisetin, particularly relevant in flavonoid research for increased bioavailability (Rosiak et al., 2024).
  • Fisetin combination therapy for neuropathic pain: Utilizing fisetin with other treatments like pregabalin and gabapentin shows effectiveness in managing neuropathic pain, demonstrating fisetin′s role in enhancing pain management therapies and its potential in neuropharmacology (Karabacak et al., 2024).
  • Fisetin in neurodegenerative disease research: Fisetin interacts with gut microbiota to offer a novel therapeutic approach in preventing and treating neurodegenerative diseases like Parkinson′s, underscoring its role in neuroprotective dietary interventions and the development of nutraceuticals (Yao et al., 2024).
  • Fisetin in cardiovascular disease management: Fisetin suppresses atherosclerosis in apolipoprotein E knockout mice by inhibiting ferroptosis-related oxidative stress, indicating its potential use as a therapeutic agent in cardiovascular disease through modulation of oxidative stress pathways (Jiang et al., 2024).

Informations légales

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
116003627
115969501
66068730

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