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C0470000

Carbocisteine

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

S-Carboxymethyl-L-cysteine, 3-carboxymethylthio-L-alanine

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About This Item

Formule empirique (notation de Hill):
C5H9NO4S
Numéro CAS:
638-23-3
Poids moléculaire :
179.19
Numéro Beilstein :
1725012
Numéro MDL:
MFCD00002614
Code UNSPSC :
41116107
ID de substance PubChem :
329774796
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

carbocisteine

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

N[C@@H](CSCC(O)=O)C(O)=O

InChI

1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

Clé InChI

GBFLZEXEOZUWRN-VKHMYHEASA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Carbocisteine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Li Sun et al.
Respirology (Carlton, Vic.), 15(7), 1064-1071 (2010-09-03)
Carbocysteine (S-carboxymethylcysteine) is a mucoactive drug with in vitro free radical scavenging and anti-inflammatory properties. Several clinical trials have indicated that carbocysteine reduces exacerbation rates in COPD. In the present study, the effect of carbocysteine on the airway load of
Masanori Asada et al.
Respiratory physiology & neurobiology, 180(1), 112-118 (2011-11-15)
To examine the effects of l-carbocisteine on airway infection with respiratory syncytial (RS) virus, human tracheal epithelial cells were pretreated with l-carbocisteine and infected with RS virus. Viral titer, virus RNA, and pro-inflammatory cytokine secretion, including interleukin (IL)-1 and IL-6
Yuichi Majima et al.
Auris, nasus, larynx, 39(1), 38-47 (2011-06-04)
In Japan, fourteen-membered ring macrolides, antibacterial agents, and S-carboxymethylcysteine (SCMC; carbocisteine), a mucolytic, are commonly used to treat chronic rhinosinusitis (CRS), and they are also used in combination. However, no large-scale randomized study has examined the effects of these pharmacotherapies.
Kenichiro Kudo et al.
Internal medicine (Tokyo, Japan), 52(1), 97-100 (2013-01-08)
A 32-year-old male with CATCH22 syndrome presented with a high fever and productive cough after taking drugs for acute bronchitis, including (L)-carbocisteine. Chest radiography revealed ground-glass opacities in the bilateral lung fields. He had a history of similar pneumonia. Under
Drug fever due to S-carboxymethyl-L-cystein: demonstration of a causative agent with patch tests.
Mayumi Hatakeyama et al.
The Journal of dermatology, 39(6), 555-556 (2011-09-29)
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