77608

Phénol

BioUltra, for molecular biology, ≥99.5% (GC)

• Synonyme(s) : Hydroxybenzène
• Formule linéaire : C₆H₅OH
• Numéro CAS: 108-95-2
• Poids moléculaire : 94.11
• Numéro Beilstein : 969616
• Numéro CE : 203-632-7
• Numéro MDL: MFCD00002143
• Code UNSPSC : 12352104
• ID de substance PubChem : 329767806
• Nomenclature NACRES : NA.25

Propriétés

• Qualité: for molecular biology
• Niveau de qualité: 100
• Densité de vapeur: 3.24 (vs air)
• Pression de vapeur: 0.09 psi ( 55 °C); 0.36 mmHg ( 20 °C)
• Gamme de produits: BioUltra
• Pureté: ≥99.5% (GC)
• Forme: solid
• Température d'inflammation spontanée: 1319 °F
• Contient: ~0.15% hypophosphorous acid as stabilizer
• Limite d'explosivité: 8.6 %
• Impuretés: DNases, none detected; RNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected; ≤0.5% water
• Résidus de calcination: ≤0.05%
• pH: 3.0-6.0 (25 °C, 0.5 M in H₂O)
• Point d'ébullition: 182 °C (lit.)
• Pf: 40-42 °C (lit.); 40-42 °C
• Solubilité: H₂O: 0.5 M at 20 °C, clear, colorless
• Densité: 1.071 g/mL at 25 °C (lit.)
• Traces d'anions: chloride (Cl^-): ≤5 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• Traces de cations: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• Chaîne SMILES: Oc1ccccc1
• Absorption: cut-off at 294 nm in H₂O at 0.5 M
• Adéquation: suitable for molecular biology
• Température de stockage: 2-8°C
• InChI: 1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H
• Clé InChI: ISWSIDIOOBJBQZ-UHFFFAOYSA-N

Description

Description générale

Phenol/carbolic acid is mainly produced by hospital pharmacy as it is unavailable in premixed liquid form. It is not highly soluble in water. Phenol should be refrigerated and protected from light exposure to maintain its shelf life of approximately one year. Kidneys can excrete phenol as several conjugated derivatives.

Application

Phenol has been used in the incubation of pellet for RNA extraction.

Actions biochimiques/physiologiques

Phenol has the ability to denature protein, hence can lead to denervation. At lower concentration, it can serve as a local anaesthetic and can also act as a neurolytic agent in higher concentration. It is also linked with tissue damage at higher concentrations.

Autres remarques

For the preparation of DNA ; Large- and small-scale phenol extractions

Informations sur la sécurité

• Pictogrammes: GHS05,GHS06,GHS08,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H301 + H311 + H331 - H314 - H341 - H373 - H411
• Conseils de prudence: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2
• Code de la classe de stockage: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 174.2 °F - closed cup
• Point d'éclair (°C): 79.0 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges