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50194

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Sulisobenzone

analytical standard

Synonyme(s) :

5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid, HMBS, Sulisobenzone

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About This Item

Formule empirique (notation de Hill):
C14H12O6S
Numéro CAS:
4065-45-6
Poids moléculaire :
308.31
Numéro Beilstein :
2889165
Numéro CE :
223-772-2
Numéro MDL:
MFCD00024962
Code UNSPSC :
41116107
ID de substance PubChem :
329757575
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

100

Pureté

≥97.5% (HPLC)

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

Format

neat

Chaîne SMILES 

COc1cc(O)c(cc1S(O)(=O)=O)C(=O)c2ccccc2

InChI

1S/C14H12O6S/c1-20-12-8-11(15)10(7-13(12)21(17,18)19)14(16)9-5-3-2-4-6-9/h2-8,15H,1H3,(H,17,18,19)

Clé InChI

CXVGEDCSTKKODG-UHFFFAOYSA-N

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Description générale

Sulisobenzone is a broad spectrum organic UV filter in sunscreen formulations, known to absorb deleterious UV light.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulisobenzone may be used as an analytical reagent for the determination of the analyte in sunscreen formulations by high-performance liquid chromatography with UV spectrophotometric detection.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H412

Classification des risques

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

No data available

Point d'éclair (°C)

No data available

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Certificats d'analyse (COA)

Lot/Batch Number
BGBC3807V
BGBC3806V
BGBC3805V
BGBC3804V
BCBH0992V

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Determination of UV-filters in sunscreens by HPLC.
Chisvert A, et al.
Fresenius Journal of Analytical Chemistry, 369(7-8), 638-641 (2001)
S M Edwards et al.
Photodermatology, photoimmunology & photomedicine, 10(3), 111-117 (1994-06-01)
The ability to accurately predict the phototoxic potential of personal and skin care products remains a key element in assessing the safety of premarketed products. To find a reliable in vitro alternative test for photoirritancy, the European Commission and the
M Jarratt et al.
Journal of the American Academy of Dermatology, 9(3), 354-360 (1983-09-01)
A PABA ester-oxybenzone preparation is superior to PABA or sulisobenzone alone in protecting the skin from methoxsalen-induced ultraviolet A (UVA) phototoxicity after water substantivity challenge. Such a mixture would be useful as a UVA screen for uninvolved or actinically damaged
C Augustin et al.
Photodermatology, photoimmunology & photomedicine, 13(1-2), 27-36 (1997-02-01)
Phototoxicity inducing in vivo photoirritation, a reversible inflammatory reaction of the skin after chemical contact and UVA radiation exposure, is increasingly observed as a side effect associated with the use of both cosmetics and systemic drugs. In order to systematically
Zacarías León et al.
Analytica chimica acta, 664(2), 178-184 (2010-04-07)
2-Hydroxy-4-methoxybenzophenone and 2-hydroxy-4-methoxybenzophenone-5-sulphonic acid, commonly known as benzophenone-3 (BZ3) and benzophenone-4 (BZ4), respectively, are substances widely used as UV filters in cosmetic products in order to absorb UV radiation and protect human skin from direct exposure to the deleterious wavelengths
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