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Key Documents

34039

Supelco

Marbofloxacin

VETRANAL®, analytical standard

Synonyme(s) :

Zeniquin®

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About This Item

Formule empirique (notation de Hill):
C17H19FN4O4
Numéro CAS:
Poids moléculaire :
362.36
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

Gamme de produits

VETRANAL®

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN4N(C)COc2c34)C(O)=O

InChI

1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)

Clé InChI

BPFYOAJNDMUVBL-UHFFFAOYSA-N

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Description générale

Marbofloxacin belongs to the group of synthetic fluoroquinolone compounds, widely used as a veterinary anti-bacterial drug. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria.

Application

The analytical standard can be used as follows:
  • Surface-enhanced Raman spectroscopy-based determination of marbofloxacin in chicken and duck samples using β-cyclodextrin-modified silver nanoparticles (β-CD-AgNPs)
  • Analysis of synovial fluid and plasma samples obtained from dairy cows for marbofloxacin by high-performance liquid chromatography (HPLC) combined with tandem mass spectrometry (MS/MS) following ultrafiltration of the samples
  • Development of an indirect competitive ELISA (icELISA) method for the combined analysis of marbofloxacin and ofloxacin in raw milk and porcine samples
  • Multi-residue analysis of oxolinic acid, flumequine, marbofloxacin, and enrofloxacin in commercial honey samples by micellar liquid chromatography coupled with fluorescence detection
  • Simultaneous determination of marbofloxacin and trovafloxacin in sheep plasma samples by HPLC combined with UV detection
  • Quantification of marbofloxacin in plasma samples by high-performance liquid chromatography using fluorescence detection.

Autres remarques

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Zeniquin is a registered trademark of Pfizer, Inc.

Mentions de danger

Conseils de prudence

Classification des risques

Aquatic Chronic 3

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Équipement de protection individuelle

Gloves


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Blood concentrations of marbofloxacin and its in vivo effect in yellow-bellied slider turtles (Trachemys scripta scripta) after a single intracoelomic injection at 3 dose rates.
Vercelli C, et al.
Journal of Exotic Pet Medicine, 25(4), 295-304 (2016)
Determination of marbofloxacin in plasma samples by high-performance liquid chromatography using fluorescence detection.
Garcia M A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 729(1-2), 157-161 (1999)
C Vilalta et al.
Journal of veterinary pharmacology and therapeutics, 37(6), 542-549 (2014-06-07)
This study evaluated the theoretical clinical outcome of three marbofloxacin posology regimens in two groups of pigs (weaners and fatteners) for the treatment of Actinobacillus pleuropneumoniae (App) and Haemophilus parasuis (Hp) infection and the appearance of resistant bacteria due to
Xiaoqiang Liu et al.
Veterinary microbiology, 174(3-4), 514-522 (2014-12-04)
This study explored and compared the mechanisms and selective concentration of resistance between a 3rd (pradofloxacin) and 2nd (ciprofloxacin) generation fluoroquinolone. Pradofloxacin- and ciprofloxacin-resistant mutants were selected by stepwise exposure of Escherichia coli (E. coli) to escalating concentrations of pradofloxacin
Seung Ryul Han et al.
Biochemical and biophysical research communications, 448(4), 397-402 (2014-05-06)
Danofloxacin is a synthetic fluoroquinolone with broad spectrum antibacterial activity that is used for the treatment of respiratory diseases in animal husbandry. However, danofloxacin has many adverse reactions and is toxic to humans. Especially, it detrimentally affects muscle, central nerve

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