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Sterigmatocystin

Name: Sterigmatocystin
Brand: SIAL

Synonyme(s) :

3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furol[3′,2′:4,5]furo[2,3-c]xanthen-7-one

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About This Item

Formule empirique (notation de Hill):

C₁₈H₁₂O₆

Numéro CAS:

10048-13-2

Poids moléculaire :

324.28

Numéro Beilstein :

53259

Numéro CE :

233-158-6

Numéro MDL:

MFCD00005084

Code UNSPSC :

85151701

ID de substance PubChem :

329754270

Nomenclature NACRES :

NA.24

Qualité

analytical standard
reference material

Fabricant/nom de marque

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

cleaning products
cosmetics
food and beverages
personal care

Format

neat

Température de stockage

−20°C

Chaîne SMILES

COc1cc2OC3OC=CC3c2c4Oc5cccc(O)c5C(=O)c14

InChI

1S/C18H12O6/c1-21-11-7-12-13(8-5-6-22-18(8)24-12)17-15(11)16(20)14-9(19)3-2-4-10(14)23-17/h2-8,18-19H,1H3

Clé InChI

UTSVPXMQSFGQTM-UHFFFAOYSA-N

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Description générale

Sterigmatocystin is classified under the mycotoxin family of compounds that is usually produced by fungi of several species of Aspergillus.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sterigmatocystin may be used as an analytical reference standard for the determination of the analyte in:

Grain samples by high-performance liquid chromatography-electrospray positive ionization-tandem mass spectrometry (HPLC-ESI⁺-MS/MS).
Sweet pepper samples by LC-ESI⁺-MS/MS.

Actions biochimiques/physiologiques

Initiates lung and liver tumors under experimental conditions.

Pictogrammes

GHS06,GHS08

Mention d'avertissement

Danger

Mentions de danger

H301,H351

Conseils de prudence

P201 - P301 + P310 + P330

Classification des risques

Acute Tox. 3 Oral - Carc. 2

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Multiresidue mycotoxin analysis in wheat, barley, oats, rye and maize grain by high-performance liquid chromatography-tandem mass spectrometry.

Martos P, et al.

World Mycotoxin Journal, 3(3), 205-223 (2010)

Development of a multi-mycotoxin liquid chromatography/tandem mass spectrometry method for sweet pepper analysis.

Monbaliu S, et al.

Rapid Communications in Mass Spectrometry, 23(1), 3-11 (2009)

Analytical method for the determination of sterigmatocystin in grains using high-performance liquid chromatography-tandem mass spectrometry with electrospray positive ionization.

Ver?ilovskis A, et al.

Journal of Chromatography A, 1157(1-2), 467-471 (2007)

Effects of low molecular weight fungal compounds on inflammatory gene transcription and expression in mouse alveolar macrophages.

Thomas G Rand et al.

Chemico-biological interactions, 190(2-3), 139-147 (2011-03-02)

The inflammatory potential and molecular mechanisms underscoring inflammatory responses of lung cells to compounds from fungi that grow on damp building materials is poorly understood in vitro. In this study we evaluated the effect of pure fungal compounds on potentiating

Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells.

Xin Xing et al.

Molecular nutrition & food research, 55(5), 749-760 (2011-02-03)

Sterigmatocystin (ST), a mycotoxin commonly found in foodstuff and feedstuff, has been shown to be a carcinogenic mycotoxin in animal models. Many studies showed that the high level of ST contamination in grains might be related to the high incidence

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