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131105

Sigma-Aldrich

3,6-Diaminoacridine hydrochloride

Dye content 95 %

Synonyme(s) :

Proflavine hydrochloride, Proflavine monohydrochloride

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About This Item

Formule empirique (notation de Hill):
C13H11N3 · HCl
Numéro CAS:
Poids moléculaire :
245.71
Numéro CE :
Numéro MDL:
Code UNSPSC :
12171500
ID de substance PubChem :
Nomenclature NACRES :
NA.47

Pureté

94.0% (HPLC)

Forme

powder

Composition

Dye content, 95%

Pf

270 °C (dec.) (lit.)

Solubilité

H2O: 1 mg/mL, clear

λmax

456 nm

ε (coefficient d'extinction)

50000 at 260 nm in methanol

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

Chaîne SMILES 

Cl[H].Nc1ccc2cc3ccc(N)cc3nc2c1

InChI

1S/C13H11N3.ClH/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;/h1-7H,14-15H2;1H

Clé InChI

PBBGTVBGXBUVLT-UHFFFAOYSA-N

Application

3, 6-Diaminoacridine hydrochloride has been used for studying cation transfer at the liquid–liquid interface.
An intercalating dye.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Les clients ont également consulté

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1 of 1

Membrane activity of ionisable drugs ? a task for liquid?liquid electrochemistry?
Malkia A
Electrochemical Communications, 5:6, 473-479 (2003)
Miklós Nagy et al.
Scientific reports, 9(1), 8250-8250 (2019-06-05)
Amino-isocyanoacridines (ICAAcs), as first members of their class, turned out to be a novel, multifunctional acridine orange (AO) type dye family with a number of additional favorable properties. They have enhanced solvatochromic emission range, low quantum yields (ΦF = 2.9-0.4%) in water
Anirban Basu et al.
Journal of photochemistry and photobiology. B, Biology, 165, 42-50 (2016-10-22)
Interaction of proflavine with hemoglobin (Hgb) was studied employing spectroscopy, calorimetry, and atomic force microscopy. The equilibrium constant was found to be of the order 10
Anna Porfireva et al.
Nanomaterials (Basel, Switzerland), 10(5) (2020-05-14)
A DNA sensor has been developed for the determination of doxorubicin by consecutive electropolymerization of an equimolar mixture of Azure B and proflavine and adsorption of native DNA from salmon sperm on a polymer film. Electrochemical investigation showed a difference
Anirban Basu et al.
Journal of biomolecular structure & dynamics, 38(6), 1590-1597 (2019-05-07)
The binding of proflavine, an acriflavine derivative, with the RNA polynucletodide polyadenylic acid-polyuridylic acid is investigated here to understand the structural and thermodynamic basis of the binding process. Such binding data are crucial for designing viable theraperutic agents. Spectroscopic studies

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