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Key Documents

30-4310

Sigma-Aldrich

Acide trifluoroacétique

SAJ special grade, ≥99.0%

Synonyme(s) :

TFA

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About This Item

Formule linéaire :
CF3COOH
Numéro CAS:
Poids moléculaire :
114.02
Numéro Beilstein :
742035
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352106
ID de substance PubChem :

Qualité

SAJ special grade

Densité de vapeur

3.9 (vs air)

Pression de vapeur

97.5 mmHg ( 20 °C)

Pureté

≥99.0%

Forme

liquid

Disponibilité

available only in Japan

Indice de réfraction

n20/D 1.3 (lit.)

pH

1 (20 °C, 1 g/L)

Point d'ébullition

72.4 °C (lit.)

Pf

−15.4 °C (lit.)

Solubilité

H2O: soluble

Densité

1.489 g/mL at 20 °C (lit.)

Chaîne SMILES 

OC(C(F)(F)F)=O

InChI

1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

Clé InChI

DTQVDTLACAAQTR-UHFFFAOYSA-N

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Application


  • New fabric phase sorptive extraction for nondestructive analysis of heritage textile samples.: This study introduces a novel extraction method utilizing trifluoroacetic acid for analyzing heritage textiles without causing damage. The technique improves the efficiency and accuracy of detecting and quantifying analytes in historical fabrics (Tanasescu et al., 2024).

  • Alpibectir: Early Qualitative and Quantitative Metabolic Profiling from a First Time in Human Study by Combining (19)F-NMR, (1)H-NMR and HRMS Analyses.: This research employs trifluoroacetic acid in metabolic profiling to enhance the resolution and accuracy of NMR and HRMS analyses, providing critical insights into the early stages of drug metabolism (Weston et al., 2024).

  • Preparation and characterization of stationary phase gradients on C8 liquid chromatography columns.: The use of trifluoroacetic acid in preparing stationary phase gradients significantly improves the performance and stability of C8 columns in liquid chromatography, optimizing the separation of complex mixtures (Cecil et al., 2024).

  • Optimization of Cyanocobalamin (Vitamin B(12)) Sorption onto Mesoporous Superparamagnetic Iron Oxide Nanoparticles.: This article details the use of trifluoroacetic acid in the optimization process of sorbing vitamin B12 onto nanoparticles, enhancing the efficacy of nutrient delivery systems (Flieger et al., 2024).

  • Development, Validation, and Application of High-Performance Liquid Chromatography with Diode-Array Detection Method for Simultaneous Determination of Ginkgolic Acids and Ginkgols in Ginkgo biloba.: Trifluoroacetic acid is utilized in this method development for HPLC, enabling accurate and simultaneous determination of multiple compounds in Ginkgo biloba extracts (Boateng et al., 2024).

Pictogrammes

CorrosionExclamation mark

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

>212.0 °F - Pensky-Martens closed cup

Point d'éclair (°C)

> 100 °C - Pensky-Martens closed cup


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Consulter la Bibliothèque de documents

Guillaume Plourde et al.
Lancet (London, England), 386(10009), 2192-2203 (2015-09-29)
Transradial access for cardiac catheterisation results in lower bleeding and vascular complications than the traditional transfemoral access route. However, the increased radiation exposure potentially associated with transradial access is a possible drawback of this method. Whether transradial access is associated
Yukiko Enomoto-Rogers et al.
Carbohydrate polymers, 92(2), 1827-1834 (2013-02-13)
Fully substituted glucomannan triacetate (GMTAc) (degree of substitution (DS)=3.0) was prepared from konjac glucomannan (KGM) treated with acetic acid and trifluoroacetic anhydride (TFAA). The peaks in the (1)H- and (13)C NMR spectra of GMTAc were assigned in detail based on
Wen Zhang et al.
Methods (San Diego, Calif.), 81, 50-55 (2015-02-28)
Clinical tissue samples provide valuable information for understanding human diseases. One major type of clinical tissue sample that is amenable to various kinds of analysis is fresh frozen and optimal cutting temperature (OCT)-embedded primary patient tissue. Recent advances in mass
Christian D Kelstrup et al.
Journal of proteome research, 13(12), 6187-6195 (2014-10-29)
Shotgun proteomics is a powerful technology for global analysis of proteins and their post-translational modifications. Here, we investigate the faster sequencing speed of the latest Q Exactive HF mass spectrometer, which features an ultra-high-field Orbitrap mass analyzer. Proteome coverage is
Szabolcs Fekete et al.
Journal of chromatography. A, 1393, 73-80 (2015-04-01)
The goal of this work was to evaluate the changes in retention induced by frictional heating, pressure and temperature under ultra high pressure liquid chromatography (UHPLC) conditions, for four model proteins (i.e. lysozyme, myoglobin, fligrastim and interferon alpha-2A) possessing molecular

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