Accéder au contenu
Merck
Toutes les photos(2)

Key Documents

RKTX1MAG-37K

Millipore

MILLIPLEX® Rat Kidney Toxicity Magnetic Bead Panel 1 - Toxicity Multiplex Assay

The analytes available for this multiplex kit are: Clusterin, GSTα, IP-10, KIM-1, OPN - Osteopontin, TIMP-1, VEGF.

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme


About This Item

Code UNSPSC :
12161503
eCl@ss :
32161000
Nomenclature NACRES :
NA.84

Niveau de qualité

Espèces réactives

rat

Fabricant/nom de marque

Milliplex®

assay range

accuracy: 70-123%
standard curve range: 0.03-20 ng/mL
(IP-10, KIM-1, OPN)

standard curve range: 0.03-20 ng/mL
(VEGF)

standard curve range: 0.27-200 ng/mL
(TIMP-1)

standard curve range: 2.06-1500 ng/mL
(Clusterin)

standard curve range: 4.12-3000 ng/mL
(GSTα)

inter-assay cv: <10%
intra-assay cv: <15%
(All other analytes)

inter-assay cv: <20%
intra-assay cv: <30%
(GSTα)

Technique(s)

multiplexing: suitable

Méthode de détection

fluorometric (Luminex xMAP)

Conditions d'expédition

wet ice

Description générale

MILLIPLEX® Rat Kidney Toxicity Bead Panels 1 & 2, coupled with the Luminex® xMAP®platform in a bead format, enables you to focus on discovery so you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of multiple analytes simultaneously, dramatically improving productivity.

Panel Type: Toxicity

Application

  • Analytes: Clusterin GSTα IP-10 KIM-1 OPN - Osteopontin TIMP-1 VEGF
  • Recommended Sample type: urine
  • Recommended Sample dilution: 1:2
  • Assay Run Time: Overnight

Caractéristiques et avantages

Design your multiplex kit by choosing available analytes within this panel.

Autres remarques

Sensitivity: See kit protocol for individual analytes sensitivities.

Informations légales

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Pictogrammes

Skull and crossbonesEnvironment

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Javad Habibi et al.
Cardiovascular diabetology, 18(1), 40-40 (2019-03-27)
Diabetic nephropathy (DN) is characterized by glomerular and tubulointerstitial injury, proteinuria and remodeling. Here we examined whether the combination of an inhibitor of neprilysin (sacubitril), a natriuretic peptide-degrading enzyme, and an angiotensin II type 1 receptor blocker (valsartan), suppresses renal
Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance.
Wunnapuk, K; Liu, X; Gobe, GC; Endre, ZH; Peake, PW; Grice, JE; Roberts, MS; Buckley, NA
Toxicology Letters null
Iwan P Williams et al.
mAbs, 12(1), 1685349-1685349 (2019-11-27)
IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and
Nadeeka S Udawatte et al.
Frontiers in pharmacology, 11, 511-511 (2020-05-12)
Candida albicans is the major fungal species associated with superficial mucosal infections such as oral candidiasis as well as systemic mycoses with high morbidity and mortality. On top of the rising drug resistance, currently available antifungal agents have significant adverse
Klintean Wunnapuk et al.
Toxicology letters, 225(1), 192-200 (2013-12-24)
Accidental or intentional ingestion of glyphosate surfactant-based herbicides, like Roundup(®), leads to nephrotoxicity as well as death. In this study, a panel of kidney injury biomarkers was evaluated in terms of suitability to detect acute kidney injury and dysfunction. The

Contenu apparenté

Novel kidney toxicity biomarkers expand options for acute nephrotoxicity detection. Multiplex assays measure multiple renal damage biomarkers in small sample volumes, minimizing time and costs. See how MILLIPLEX® multiplex kidney toxicity assays detected vancomycin-induced subacute nephrotoxicity in rat models.

Learn the benefits of using biomarker detection multiplex immunoassays for laboratory, companion, and agricultural animal research and explore MILLIPLEX® multiplex assays for veterinary medicine and animal health research.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique