MABT167

Anti-Transgelin/SM22a Antibody, clone 20F2.2

clone 20F2.2, from mouse

• Synonyme(s) : Transgelin, 22 kDa actin-binding protein, Protein WS3-10, Smooth muscle protein 22-alpha, SM22-alpha, SM22a
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 20F2.2, monoclonal
• Espèces réactives: human, mouse, rat
• Technique(s): immunocytochemistry: suitable; western blot: suitable
• Isotype: IgG1κ
• Numéro d'accès NCBI: NP_001001522
• Numéro d'accès UniProt: Q01995
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... TAGLN(6876)

Description

Description générale

Transgelin, also known as 22 kDa actin-binding protein, Protein WS3-10, and Smooth muscle protein 22-alpha (SM22-alpha), is an actin cross-linking protein that is involved in cellular calcium interactions and contractile properties of the cytoskeleton contributing to replication and senescence in smooth muscle tissue. Transgelin is overexpressed in senescent human fibroblasts.

Immunogène

GST-tagged recombinant protein corresponding to human Transgelin/SM22a.

Application

Anti-Transgelin/SM22a Antibody, clone 20F2.2 is a highly specific mouse monoclonal antibody, that targets Transgelin & has been tested in western blotting & ICC.

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

Western Blotting Analysis: 1 µg/ml from a representative lot detected Transgelin/SM22a in 10 µg of NIH/3T3 and PC12 cell lysates.

Immunocytochemistry Analysis: A 1:50 dilution from a representative lot detected Transgelin/SM22a in NIH/3T3 cells.

Qualité

Evaluated by Western Blotting in U20S cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected Transgelin/SM22a in 10 µg of U20S cell lysate.

Description de la cible

~22 kDa observed

Forme physique

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
U20S cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable