487950

NOC-5

A nitric oxide (NO) donor.

• Synonyme(s) : NOC-5, 3-[2-Hydroxy-1-(1-methylethyl)-2-nitrosohydrazino]-1-propanamine
• Formule empirique (notation de Hill): C₆H₁₆N₄O₂
• Numéro CAS: 146724-82-5
• Poids moléculaire : 176.22
• Numéro MDL: MFCD00274389
• Code UNSPSC : 12352200

Propriétés

• Niveau de qualité: 100
• Pureté: ≥95% (HPLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated (hygroscopic); protect from light
• Couleur: white
• Solubilité: 0.1 M NaOH: soluble; water: soluble
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• InChI: 1S/C6H16N4O2/c1-6(2)9(5-3-4-7)10(12)8-11/h6,12H,3-5,7H2,1-2H3
• Clé InChI: WEHZRCACNLQADC-UHFFFAOYSA-N

Description

Description générale

A nitric oxide (NO) donor. A stable NO-amine complex that can release two equivalents of NO spontaneously in solution under physiological conditions without a cofactor. Half-life (t_½) of NO release is 93 min (PBS, pH 7.4, 22°C).

A nitric oxide (NO) donor. A stable NO-amine complex that can spontaneously release two equivalents of NO in solution under physiological conditions without any cofactor. Half-life (t_½) in PBS, pH 7.4 is 93 minutes at 22°C. Relatively stable in alkaline solution (pH ≥10.0).

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
A nitric oxide (NO) donor

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Irritant (B)

Reconstitution

Following reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O just prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.

Autres remarques

Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02
• Mention d'avertissement: Danger
• Mentions de danger: H242
• Conseils de prudence: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Classification des risques: Self-react. C
• Code de la classe de stockage: 5.2 - Organic peroxides and self-reacting hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable