14-452-M

PDK1 Protein, active, 10 µg

Active, N-terminal, His6-tagged, recombinant human PDK1, amino acids 52-end. For use in Kinase Assays.

• Code UNSPSC : 12352202
• eCl@ss : 32160405
• Nomenclature NACRES : NA.26

Propriétés

• Source biologique: human
• Niveau de qualité: 100
• Produit recombinant: expressed in baculovirus infected Sf21 cells
• Gamme de produits: Upstate^®
• Activité spécifique: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
• Poids mol.: M_w 59 kDa
• Produit purifié par: (Ni²⁺/NTA-agarose)
• Espèces réactives: human
• Fabricant/nom de marque: Upstate^®
• Technique(s): activity assay: suitable (kinase)
• Numéro d'accès: (FUNCTION: SwissProt: O15530 # Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive. ); NM_002613.3
• Numéro d'accès NCBI: NM_002613.3; NM_031268.4
• Numéro d'accès UniProt: O15530
• Informations sur le gène: human ... PDPK1(5170)

Description

Description générale

N-terminal, His6-tagged, recombinant human PDK1, amino acids 52-end.

Actions biochimiques/physiologiques

Protein Target: PDK1

Target Sub-Family: AGC

Conditionnement

Also available in 10 μg size and in bulk

Also available in 250 µg size --call for pricing and availability and reference catalog number 14-452M when ordering the 250 µg size.

Qualité

Routinely evaluated by phosphorylation of PDKtide

Description de la cible

PDK1

Forme physique

50mM Tris-HCl, pH 7.5, 0.15M NaCl, 0.1mM EGTA, 0.03% Brij-35, 0.1% 2-mercaptoethanol, 1mM benzamidine, 200μM PMSF and 5% glycerol

Ni²⁺/NTA-agarose

Stockage et stabilité

6 months at -70°C

Autres remarques

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H317
• Conseils de prudence: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classification des risques: Skin Sens. 1
• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°C): Not applicable