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Merck
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Principaux documents

05-579

Sigma-Aldrich

Anti-Endostatin Antibody, clone 1837.46

clone 1837.46, Upstate®, from mouse

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

1837.46, monoclonal

Espèces réactives

mouse, human

Fabricant/nom de marque

Upstate®

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

mouse ... Col18A1(12822)

Spécificité

endostatin

Immunogène

Full-length recombinant murine endostatin

Application

Anti-Endostatin Antibody, clone 1837.46 is an antibody against Endostatin for use in WB, IH.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Qualité

routinely evaluated by immunoblot on 3T3 cell lysates

Description de la cible

Recognizes endostatin, Mr 22kDa An unidentified protein is also weakly detected at Mr 54kDa

Forme physique

50mM sodium phosphate, pH 8.0, 0.05% sodium azide, before the addition of glycerol to 30%
Format: Purified
Thiophilic chromatography

Stockage et stabilité

2 years at -20°C

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1


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Consulter la Bibliothèque de documents

H M Strik et al.
Cancer, 91(5), 1013-1019 (2001-03-17)
Endostatin is a potent inhibitor of endothelial cell proliferation, angiogenesis, and tumor growth. Its occurrence and localization has not yet been examined in human brain tumors. The authors report the production of a monoclonal antibody and detection of endostatin in
M Dhanabal et al.
The Journal of biological chemistry, 274(17), 11721-11726 (1999-04-17)
Endostatin, a carboxyl-terminal fragment of collagen XVIII, has been shown to regress tumors in mice. In this study, we have analyzed the mechanism of endostatin action on endothelial cells and nonendothelial cells. Endostatin treatment of cow pulmonary artery endothelial cells
B V Sauter et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(9), 4802-4807 (2000-04-12)
Inhibition of angiogenesis has been shown to be an effective strategy in cancer therapy in mice. However, its widespread application has been hampered by difficulties in the large-scale production of the antiangiogenic proteins. This limitation may be resolved by in
Induction of the RNA regulator LIN28A is required for the growth and pathogenesis of RESTless breast tumors.
Gunsalus, KT; Wagoner, MP; Meyer, K; Potter, WB; Schoenike, B; Kim, S; Alexander et al.
Cancer Research null
M C Cichy et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 42(12), 1150-1155 (2009-11-07)
Acute renal failure (ARF) is a frequent complication of Gram-negative sepsis, with a high risk of mortality. Lipopolysaccharide (LPS)-induced ARF is associated with hemodynamic changes that are strongly influenced by the overproduction of nitric oxide (NO) through the cytokine-mediated up-regulation

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