V-027

(±)-O-Desmethylvenlafaxine-D₆ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonyme(s) : (±)−O-Desmethylvenlafaxine-D₆ solution
• Formule empirique (notation de Hill): C₁₆H₁₉D₆NO₂
• Numéro CAS: 1062605-69-9
• Poids moléculaire : 269.41
• Numéro CE : 200-659-6
• Numéro MDL: MFCD07369295
• Code UNSPSC : 41116107
• ID de substance PubChem : 329828969
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Forme: liquid
• Caractéristiques: (Snap-N-Spike^®)
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 100 μg/mL in methanol
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): clinical testing
• Format: single component solution
• Température de stockage: −20°C
• Chaîne SMILES: OC1=CC=C(C(CN(C([2H])([2H])[2H])C([2H])([2H])[2H])C2(O)CCCCC2)C=C1
• InChI: 1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3/i1D3,2D3
• Clé InChI: KYYIDSXMWOZKMP-WFGJKAKNSA-N

Description

Description générale

A certified reference solution suitable for use as an internal standard for quantitation of O-desmethylvenlafaxine levels in urine or isotope dilution methods by LC/MS or GC/MS for clinical toxicology, urine drug testing, or forensic analysis. Also known as desvenlafaxine, O-desmethylvenlafaxine is an SNRI antidepressant marketed under the trade name Pristiq^® for treatment of depression. O-desmethylvenlafaxine is also a major urinary metabolite of venlafaxine, an SNRI antidepressant sold as Effexor^® or Efexor and used to treat major depressive disorder, generalized anxiety disorder, and other anxiety disorders associated with depression.

Application

• Hydrodesulfurization research using pharmacosiderite Mo(4)P(3)O(16): This study utilized the microporous catalytic activity of synthesized Mo(4)P(3)O(16) under moderate temperatures for hydrodesulfurization, showing its potential in refining processes relevant to forensic toxicology for substance identification, including antidepressant drug metabolites (Ishikawa et al., 2024).
• Synthesis of acyl cyclopentaquinolinones: Research demonstrated the construction of acyl cyclopentaquinolinones with potential implications for the synthesis and analysis of stable isotope-labeled compounds, helping to understand the biochemistry and metabolism of antidepressants (Xue et al., 2024).
• Nutraceutical applications from biomass: The production and characterization of xylooligosaccharides from lignocellulosic biomass were reviewed, relevant for pharmacokinetic research by providing insights into plant-derived compound processing and applications, influencing stable isotope-labeled compound studies (Kumar et al., 2024).
• Adverse event detection in pharmaceutical care: This study evaluated deep learning models for detecting adverse events from pharmaceutical care records, offering a methodological approach that could be adapted for monitoring effects related to antidepressant drugs in clinical settings (Nishioka et al., 2024).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Effexor is a registered trademark of American Home Product Corp.

Pristiq is a registered trademark of Wyeth LLC

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 49.5 °F
• Point d'éclair (°C): 9.7 °C