P-121

Prednisolone solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Formule empirique (notation de Hill): C₂₁H₂₈O₅
• Numéro CAS: 50-24-8
• Poids moléculaire : 360.44
• Numéro MDL: MFCD00003649
• Code UNSPSC : 41116107
• ID de substance PubChem : 329820079
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 100 μg/mL in acetonitrile
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): clinical testing
• Format: single component solution
• Température de stockage: −20°C
• InChI: 1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• Clé InChI: OIGNJSKKLXVSLS-VWUMJDOOSA-N
• Informations sur le gène: human ... NR3C1(2908)

Description

Description générale

Prednisolone is a synthetic glucocorticoid and derivative of cortisol which is used to treat a variety of inflammatory and auto-immune conditions. It is the active metabolite of the drug prednisone and is used especially in patients with liver failure, as these individuals are unable to metabolise prednisone into prednisolone. This Certified Spiking Solution^® is suitable for use as starting materials in the preparation of calibrators and controls for prednisolone testing methods by GC/MS or LC-MS/MS.

Application

• Casein hydrolysate as a rapid and/or enteric dissolving additive for oral drugs.: This study investigates the use of Prednisolone solution in formulating rapid and enteric dissolving oral drugs. It highlights the importance of Prednisolone liquid for biochemical assays and in vitro glucocorticoid studies, demonstrating its utility in pharmaceutical research applications (Imai et al., 1998).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H225 - H302 + H312 + H332 - H319
• Conseils de prudence: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 35.6 °F - closed cup
• Point d'éclair (°C): 2.0 °C - closed cup