M-132

N-Méthyl-N-(triméthylsilyl)trifluoroacétamide

ampule of 10 × 1.2 mL, analytical standard, Cerilliant^®

• Synonyme(s) : N-Triméthylsilyl-N-méthyl trifluoroacétamide, MSTFA
• Formule linéaire : CF₃CON(CH₃)Si(CH₃)₃
• Numéro CAS: 24589-78-4
• Poids moléculaire : 199.25
• Numéro Beilstein : 1941550
• Numéro CE : 246-331-6
• Numéro MDL: MFCD00000411
• Code UNSPSC : 41116107
• ID de substance PubChem : 329817869
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Densité de vapeur: >1 (vs air)
• Pression de vapeur: 8.8 mmHg ( 27 °C)
• Pertinence de la réaction: reagent type: derivatization reagent; reaction type: Acylations
• Conditionnement: ampule of 10 × 1.2 mL
• Fabricant/nom de marque: Cerilliant^®
• Technique(s): gas chromatography (GC): suitable
• Indice de réfraction: n20/D 1.38 (lit.)
• Point d'ébullition: 130-132 °C (lit.)
• Densité: 1.075 g/mL at 25 °C (lit.)
• Application(s): forensics and toxicology
• Format: neat
• Température de stockage: −20°C
• Chaîne SMILES: CN(C(=O)C(F)(F)F)[Si](C)(C)C
• InChI: 1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3
• Clé InChI: MSPCIZMDDUQPGJ-UHFFFAOYSA-N

Description

Description générale

MSTFA (N-Methyl-N-trimethylsilylfluoroacetamide) is an important trimethylsilyl reagent, and a commonly applied reagent since it is highly reactive towards a broad range of compound classes. GC-MS optimization studies reveal the use of this reagent either alone or in combination with 1% of trimethylchlorosilane as a catalyst for silylation of complex mixtures. It has similar reactivity as BSA and BSTFA.

Application

MSTFA reagent may be used as a derivatizing agent in the following:

• Analysis of estrogen steroids such as estrone (E1), 17α-ethinylestradiol (EE2), and trenbolone acetate metabolites, melengestrol in environmental matrices using gas chromatography coupled to mass spectrometry (GC-MS).
• Quantification of ibuprofen, naproxen, ketoprofen, and diclofenac in wastewater samples using gas chromatography coupled to mass spectrometry (GC-MS).

Caractéristiques et avantages

• Very volatile of TMS-acetamides.
• More volatile than BSA or BSTFA but with similar silylation strength.
• Useful in the analysis of volatile trace materials.
• Used in the preparation of volatile and thermally stable derivatives for GC and MS analysis.

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H226,H315,H319,H335
• Conseils de prudence: P210 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 78.8 °F - closed cup
• Point d'éclair (°C): 26 °C - closed cup