H-124

Hydroxyzine dihydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Formule empirique (notation de Hill): C₂₁H₂₇ClN₂O₂ · 2HCl
• Numéro CAS: 2192-20-3
• Poids moléculaire : 447.83
• Numéro MDL: MFCD00058200
• Code UNSPSC : 41116107
• ID de substance PubChem : 329815157
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 1.0 mg/mL in methanol (as free base)
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): clinical testing
• Format: single component solution
• Température de stockage: −20°C
• Chaîne SMILES: OCCOCCN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1.[H]Cl.[H]Cl
• InChI: 1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
• Clé InChI: ANOMHKZSQFYSBR-UHFFFAOYSA-N
• Informations sur le gène: human ... HRH1(3269)

Description

Description générale

Hydroxyzine is a commonly prescribed first generation antihistamine with sedative properties. This drug is a common cocaine adulterant along with lidocaine, phenacetin, and levamisole. This Certified Spiking Solution^® is suitable for use in a variety of GC/MS or LC/MS testing applications in forensic toxicology, urine drug testing, or clinical chemistry.

Application

• Antihistamine-Retinoic Acid Receptor Interaction: This publication presents a molecular dynamics simulation and genome-wide meta-analysis to explore the interactions of antihistamines like hydroxyzine dihydrochloride with the retinoic acid receptor beta (RARB), providing insights into possible biochemical pathways and therapeutic potentials (Kim et al., 2023).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes,Central nervous system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup