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Key Documents

840032C

Avanti

Brain PS

Avanti Research - A Croda Brand

Synonyme(s) :

L-α-phosphatidylserine (Brain, Porcine) (sodium salt)

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About This Item

Numéro CAS:
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

liquid

Conditionnement

pkg of 1 × 1 mL (840032C-10mg)
pkg of 1 × 2.5 mL (840032C-25mg)
pkg of 1 × 4 mL (840032C-100mg)

Fabricant/nom de marque

Avanti Research - A Croda Brand

Concentration

10 mg/mL (840032C-10mg)
10 mg/mL (840032C-25mg)
25 mg/mL (840032C-100mg)

Type de lipide

phosphoglycerides

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H80NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,38-39H,3-17,19,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b20-18-;/t38-,39+;/m1./s1

Clé InChI

ALPKKMIPHGSQRX-NJZWBUMZSA-M

Description générale

Phosphatidylserine (PS) is a natural phospholipid nutrient, which is located in the brain, lungs, heart, liver and skeletal muscle. It is an important component of the cell membrane.

Application

Brain PS has also been used in protein-lipid overlay (PLO) assay to evaluate the binding of SEIPIN to phosphatidic acid (PA).

Actions biochimiques/physiologiques

Phosphatidylserine (PS) regulates the activity of receptors, ion channels, enzymes and signaling molecules. It is implicated in monitoring membrane fluidity. PS plays a vital role in apoptosis and blood clotting.

Conditionnement

5 mL Clear Glass Sealed Ampule (840032C-100mg)
5 mL Clear Glass Sealed Ampule (840032C-10mg)
5 mL Clear Glass Sealed Ampule (840032C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organes cibles

Central nervous system, Liver,Kidney

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

M Gangal et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(22), 12394-12399 (1999-10-27)
Although the catalytic (C) subunit of cAMP-dependent protein kinase is N-myristylated, it is a soluble protein, and no physiological role has been identified for its myristyl moiety. To determine whether the interaction of the two regulatory (R) subunit isoforms (R(I)
Sensing phosphatidylserine in cellular membranes
Kay JG and Grinstein S
Sensors, 11(2) (2011)
Human SEIPIN binds anionic phospholipids
Yan R, et al.
Developmental Cell, 47(2), 248-256 (2018)
The effects of phosphatidylserine on endocrine response to moderate intensity exercise
Starks MA, et al.
Journal of the International Society of Sports Nutrition, 5(1), 11-11 (2008)
Jung Ho Lee et al.
Biochemistry, 55(35), 4949-4959 (2016-07-28)
The interaction between α-synuclein (αS) protein and lipid membranes is key to its role in synaptic vesicle homeostasis and plays a role in initiating fibril formation, which is implicated in Parkinson's disease. The natural state of αS inside the cell

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