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Key Documents

791637C

Avanti

15:0-18:1-d7-PC

Avanti Research™ - A Croda Brand

Synonyme(s) :

1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine

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About This Item

Formule empirique (notation de Hill):
C41H73 D7 NO8 P
Numéro CAS:
2097561-16-3
Poids moléculaire :
753.09
Code UNSPSC :
41141825
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

liquid

Conditionnement

pkg of 1 × 1 mL (791637C-1mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand

Concentration

1 mg/mL (791637C-1mg)

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

15:0-18:1-d7-PC (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine) is a deuterated phospholipid. The lipid comprises phosphatidylcholine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phospholipids, in general are amphiphilic and have phosphocholine moiety attached to sn-3 position of glycerol. Phosphatidylcholine is a glycerophospholipid and is a cell membrane component.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Application

15:0-18:1-d7-PC (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphocholine) has been used:
  • as a component of extraction solvent for lipid isolation from biological samples
  • as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)
  • as an internal standard in analysis of lipids from cystic fibrosis derived cell lines

Actions biochimiques/physiologiques

Phosphatidylcholine (PC) levels are crucial for mediating various cellular processes including membrane movement and cell differentiation. A disturbance in PC levels is implicated in various metabolic disorders.

Conditionnement

2 mL Amber Glass Sealed Ampule (791637C-1mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

Souvent commandé avec ce produit

Réf. du produit
Description
Tarif

700041P

cholesterol-d7, Avanti Research™ - A Croda Brand

791638C

15:0-18:1-d7-PE, Avanti Research™ - A Croda Brand

791643C

18:1-d7 Lyso PC, Avanti Research™ - A Croda Brand

791647C

15:0-18:1-d7 DG, Avanti Research™ - A Croda Brand 791647C

791648C

15:0-18:1-d7-15:0 TG, Avanti Research™ - A Croda Brand 791648C

791639C

15:0-18:1-d7-PS, Avanti Research™ - A Croda Brand

791640C

15:0-18:1-d7-PG, Avanti Research™ - A Croda Brand 791640C

791641C

15:0-18:1-d7-PI, Avanti Research™ - A Croda Brand

791642C

15:0-18:1-d7-PA, Avanti Research™ - A Croda Brand

791644C

18:1-d7 Lyso PE, Avanti Research™ - A Croda Brand 791644C

860681P

C15 Ceramide-d7 (d18:1-d7/15:0), Avanti Research™ - A Croda Brand 860681P, powder

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organes cibles

Central nervous system, Liver,Kidney

Code de la classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

does not flash

Point d'éclair (°C)

does not flash

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Alessandra Mingione et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 54(1), 110-125 (2020-01-31)
Cystic Fibrosis (CF) is an inherited disease associated with a variety of mutations affecting the CFTR gene. A deletion of phenylalanine 508 (F508) affects more than 70% of patients and results in unfolded proteins accumulation, originating a proteinopathy responsible for
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
Luce Farine et al.
Scientific reports, 5, 16787-16787 (2015-11-19)
Phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are among the most abundant phospholipids in biological membranes. In many eukaryotes, the CDP-ethanolamine and CDP-choline branches of the Kennedy pathway represent major and often essential routes for the production of PE and PC, with

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