W218405

2,6-Di-tert-butyl-4-methylphenol

≥99%, FCC, FG

• Synonyme(s) : Butylhydroxytoluène, Hydroxytoluène butylé
• Formule linéaire : [(CH₃)₃C]₂C₆H₂(CH₃)OH
• Numéro CAS: 128-37-0
• Poids moléculaire : 220.35
• Numéro FEMA: 2184
• Numéro Beilstein : 1911640
• Numéro CE : 204-881-4
• Numéro MDL: MFCD00011644
• Code UNSPSC : 12164502
• ID de substance PubChem : 24900896
• Numéro E: E 321
• Nomenclature NACRES : NA.21

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 400
• Qualité: FG; Fragrance grade; Kosher
• Agence: follows IFRA guidelines
• Conformité réglementaire: EU Regulation 1223/2009; EU Regulation 1333/2008 & 178/2002; FCC; FDA 21 CFR 117; FDA 21 CFR 172.115
• Densité de vapeur: 7.6 (vs air)
• Pression de vapeur: <0.01 mmHg ( 20 °C)
• Pureté: ≥99%
• Forme: powder or crystals
• Température d'inflammation spontanée: 878 °F
• Point d'ébullition: 265 °C (lit.)
• Pf: 69-73 °C (lit.)
• Application(s): flavors and fragrances
• Documentation: see Safety & Documentation for available documents
• Allergène alimentaire: no known allergens
• Allergène de parfum: no known allergens
• Propriétés organoleptiques: camphoraceous
• Chaîne SMILES: Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
• InChI: 1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3
• Clé InChI: NLZUEZXRPGMBCV-UHFFFAOYSA-N
• Informations sur le gène: human ... CAPN1(823) ; rat ... Capn1(29153) , Nos1(24598)

Description

Description générale

Butylated hydroxytoluene is a synthetic phenolic compound mainly used as an antioxidant and preservative in the food industry. It is used to prevent the lipid oxidation in oils and fat-containing foods.

Application

• Role of odorant binding protein C12 in the response of Tribolium castaneum to chemical agents.: This article explores the impact of BHT on insect biochemistry, specifically how it affects the binding affinity of odorant-binding proteins in pests, providing insights into developing more effective pest control strategies (Wang et al., 2024).


• A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3-nitropropionic acid in in vitro and in vivo models.: Research includes BHT as a comparative standard in studying neuroprotective agents, underscoring its role in biochemical pathways related to oxidative stress and neuroprotection (Campos et al., 2024).


• Simultaneous Determination of Fipronil, Permethrin and their Key Related Substances in a Topical Drug Product by a Single Stability Indicating High Performance Liquid Chromatography Method.: BHT is used as an internal standard to assess the stability and integrity of pharmaceutical products, demonstrating its utility in pharmaceutical analysis (Rathnasekara et al., 2024).


• Pyrano[2,3-c]pyrazole fused spirooxindole-linked 1,2,3-triazoles as antioxidant agents: Exploring their utility in the development of antidiabetic drugs via inhibition of a-amylase and DPP4 activity.: This study utilizes BHT as a reference antioxidant to compare the efficacy of newly synthesized compounds, providing a benchmark in antioxidant research for diabetes treatment (Chahal et al., 2024).

Informations sur la sécurité

• Pictogrammes: GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H410
• Conseils de prudence: P273 - P391 - P501
• Classification des risques: Aquatic Acute 1 - Aquatic Chronic 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 260.6 °F - open cup
• Point d'éclair (°C): 127 °C - open cup
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves